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GENESIS COQ10
CoQ10 (Ubiquinone) is a powerful antioxidant and vitamin-like compound necessary for the function of cells. It is found naturally in the body and in some foods but often the body can lack enough of this potent compound. CoQ10 can begin to lower as a person ages which is why it’s become such a popular supplement. Genesis Ubiquinone also aids in the production of energy. Serving Size: 1 Capsule Serving Per Container: 30 Formula Purposes & Benefits Genesis Blends CoQ10 is formulated to support cardiovascular, immune health and antioxidant support. Our product is synthesized utilizing the latest scientific research and formulated with optimal ratios of collagen peptides to produce world class results. Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards. Formula Ingredient Deck Benefits Of Each Ingredient CoQ10 (Ubiquinone) ● Supports cardiovascular health, cellular energy production, and antioxidant support (88). ● Supports the prevention of peroxidative damage to cell membranes and reduced oxidative damage to blood vessels (88). ● Protects DNA associated oxidative damage and stabilizes cells to combat inflammation (89). ● Enhances blood flow via increased endothelial function and improved cardiac output in patients with cardiovascular disease (89). ● Supports energy production (bioenergetic pathways) via increased ATP (energy currency of the body) production in the mitochondrial respiratory chain (89). Proper Use of This Supplement Suggested Use: As a dietary supplement take one (1) capsule once a day. For best results take 20-30 min before a meal with an 8oz. glass of water, or as directed by your health care professional. Our Formula VS Other Formulas on the Market. 1. Uses third party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third party tested have been removed by FDA due to high levels of heavy metals. 2. High quality CoQ10 in a purified and efficaciously dosed formula 2. Uses cheap sources of CoQ10 that contain high amounts of fillers and heavy metals. Sources: Sarmiento, A., Diaz-Castro, J., Pulido-Moran, M., Kajarabille, N., Guisado, R., & Ochoa, J. J. (2016). Coenzyme Q10 Supplementation and Exercise in Healthy Humans: A Systematic Review. Current drug metabolism, 17(4), 345–358. https://doi.org/10.2174/1389200216666151103115654 89. Di Lorenzo, A., Iannuzzo, G., Parlato, A., Cuomo, G., Testa, C., Coppola, M., D'Ambrosio, G., Oliviero, D. A., Sarullo, S., Vitale, G., Nugara, C., Sarullo, F. M., & Giallauria, F. (2020). Clinical Evidence for Q10 Coenzyme Supplementation in Heart Failure: From Energetics to Functional Improvement. Journal of clinical medicine, 9(5), 1266. https://doi.org/10.3390/jcm9051266 * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$29.99
GENESIS PRE-BURN WORKOUT FORMULA
Used as a pre-workout supplement to promote energy, increase focus and maintain endurance. It encourages the mind and body to respond quickly during a workout and allowing more nutrition to flow through the body to your muscles. Genesis Pre Burn will not cause sleep disturbances when taken close to the end of the day. It also helps promote muscle mass development. Formula Purposes & Benefits Genesis Blends Pre-Workout fruit punch is synthesized to improve exercise performance, increase muscle protein synthesis, prevent muscle tissue breakdown, increase energy, increase cognition, enhance your pump, and take your workouts to the next level! Our product is synthesized utilizing the latest scientific research and formulated with optimal ratios of branch chain amino acids to produce world class results. Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards. Formula Ingredient Deck Benefits Of Each Ingredient Vitamin B6 pyridoxal 5'-phosphate (PLP) ● Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). ● Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). ● Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). ● May support blood sugar regulation in women with gestational diabetes (40). ● cofactor for enzymes involved in DNA metabolism (40). Niacin (Vitamin B3) ● Major B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9). ● Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9). ● Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9). ● Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9). ● Prevents pathologies(diseases) such as Pellagra and reduces prevalence of nervous anorexia, cancer, and crohn's disease (10, 11). ● Supports sensitization of tumors to radiation via apoptosis (cell death) cascade of tumor mass and improves oxygen delivery to malignant tissues (cancer cells) (12). ● Supports cognitive health by reducing age-related decline of NAD+, increasing quinolinic acid and reducing neuroinflammation (9). ● Increased niacin associated NAD+ levels have been shown to increase neurotransmission, learning and memory (9). ● Niacin reduces the prevalence of neurodegenerative pathologies by preventing mitochondrial dysfunction (9). Caffeine Anhydrous ● Optimizes energy, cognitive function, and mental alertness (24). ● Supplementation with caffeine has been shown to acutely enhance exercise performance (24). L-Citrulline Malate ● Supports cardiovascular health and exercise performance by increasing the production of l-arginine (34). ● Increases nitric oxide production, improves exercise performance, and increases blood flow to exercising skeletal muscle (35). ● Supports strength increases, exercise endurance, and recovery (34,35). ● May reduce blood pressure by increasing vascular function (34). Bioperine ● Increases absorption of amino acids and curcumin. Folate (Folic Acid) ● May support proper cell growth and DNA synthesis (65). Vitamin B-12 (Methylcobalamin) ● Metabolically active, methylated form of Vitamin B12 needed for proper DNA synthesis, folate cycle function, energy production, cognitive function, and immune health (51,53). ● Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress (51). ● May prevent vitamin b-12 deficiency diseases such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis (53). Creatine Monohydrate ● Optimizes exercise performance, muscle mass, strength, thermoregulation, recovery, and intramuscular stores of phosphocreatine (PCr) (47). ● Vital for the energy reaction of every cell in the human body as a spatial energy shuttle and energy sensor (47,50). ● Vital in bioenergetics (metabolic activity) of the brain (50). ● Fuels CD8 and CD4 T- cell-mediated immunity (immune cells) in cancer tissue (48,49). ● Supports cognition and focus via replenishment of cerebral storage of creatine (creatine in the brain) (50). ● Supports cognitive health in brain creatine deficiency associated with neurodegenerative diseases (50). ● Supports cognitive health by enhancing the facilitation of synaptic glutamate and neurotransmitter uptake (50). N-Acetyl Tyrosine ● Supports memory, cognitive flexibility, the executive function of the brain, and convergent thinking (60). ● The precursor to dopamine and is vital for dopamine synthesis in the brain (60). ● Supports cognitive function in individuals with high amounts of stress and anxiety (60,61). ● Increases dopamine levels in highly stressed individuals (60). Choline Bitrate ● Essential for cell membrane integrity, cell messaging, fat metabolism, DNA synthesis, immune support, and nervous system function (62,63). ● Serves as a methyl donor and as a precursor for the production of cell membranes (62). ● Precursor for acetylcholine (neurotransmitter) which activates receptors in the central nervous system-mediated immune responses (α7nAchR) (64). ● Lifelong choline supplementation may combat neurodegenerative diseases by reducing amyloid-β plaque load (plaques of degrading neurons) (62). ● Reduces the concentration of total homocysteine (inflammation marker) in individuals with low levels of folate and other B vitamins (B₂, B₆, and B₁₂) (62). DMAE Bitrate ● Increases acetylcholine levels in the brain. L-Theanine ● A unique non-protein amino acid found in green tea (Camellia sinensis) (53). ● Supports mood, mental clarity, and cognitive health, memory, and is a natural anti-depressant/neuroprotective agent (53). ● Aids as an antidepressant due to partial antagonism for the N-methyl-D-aspartate receptor manifesting its cognitive optimizing effects (53). ● Reduces the neuropsychiatric side effects of chronic adolescent THC exposure (54). Bacopa Monnieri ● Supports cognitive function, memory, alertness, and aids as an anti-stress agent (57). ● May combat inflammatory conditions such as asthma, bronchitis, dropsy, and rheumatism (56,59). ● Bacopa has been shown to have anti-inflammatory effects on macrophages (immune cells) and inhibits the release of IL-6 and TNF-α (inflammatory markers) from monocytes (immune cells) (58,59,). ● A promising candidate for the development of novel therapeutics that target neuroinflammation and have the potential for treating a wide range of CNS disorders including Alzheimer's disease, depression, and schizophrenia (59). Proper Use of This Supplement Suggested Use: Stir 1 rounded scoop with 6-8ounces of cold water and consume 30-45 minutes before beginning activity. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. Utilizes efficacious evidence-based dosages with optimal ratios of amino acids, nootropics, and pump enhancers to support exercise performance and recovery. 2. Use low amounts of cheap forms of amino acids, nootropics, and pump enhancers that result in poor absorption and muscle growth, recovery, and exercise performance. Sources: Guest, N. S., VanDusseldorp, T. A., Nelson, M. T., Grgic, J., Schoenfeld, B. J., Jenkins, N., Arent, S. M., Antonio, J., Stout, J. R., Trexler, E. T., Smith-Ryan, A. E., Goldstein, E. R., Kalman, D. S., & Campbell, B. I. (2021). International society of sports nutrition position stand: caffeine and exercise performance. Journal of the International Society of Sports Nutrition, 18(1), 1. https://doi.org/10.1186/s12970-020-00383-4 Barkhidarian, B., Khorshidi, M., Shab-Bidar, S., & Hashemi, B. (2019). Effects of L-citrulline supplementation on blood pressure: A systematic review and meta-analysis. Avicenna journal of phytomedicine, 9(1), 10–20. Figueroa, A., Wong, A., Jaime, S. J., & Gonzales, J. U. (2017). Influence of L-citrulline and watermelon supplementation on vascular function and exercise performance. Current opinion in clinical nutrition and metabolic care, 20(1), 92–98. https://doi.org/10.1097/MCO.0000000000000340 Bahri, S., Zerrouk, N., Aussel, C., Moinard, C., Crenn, P., Curis, E., Chaumeil, J. C., Cynober, L., & Sfar, S. (2013). Citrulline: from metabolism to therapeutic use. Nutrition (Burbank, Los Angeles County, Calif.), 29(3), 479–484. https://doi.org/10.1016/j.nut.2012.07.002 Kreider, R. B., Kalman, D. S., Antonio, J., Ziegenfuss, T. N., Wildman, R., Collins, R., … Lopez, H. L. (2017). International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. Journal of the International Society of Sports Nutrition, 14, 18. doi:10.1186/s12970-017-0173-z Di Biase, S., Ma, X., Wang, X., Yu, J., Wang, Y. C., Smith, D. J., Zhou, Y., Li, Z., Kim, Y. J., Clarke, N., To, A., & Yang, L. (2019). Creatine uptake regulates CD8 T cell antitumor immunity. The Journal of experimental medicine, 216(12), 2869–2882. https://doi.org/10.1084/jem.20182044 Kazak, L., & Cohen, P. (2020). Creatine metabolism: energy homeostasis, immunity and cancer biology. Nature reviews. Endocrinology, 16(8), 421–436. https://doi.org/10.1038/s41574-020-0365-5 Ebrahimi, K., Jourkesh, M., Sadigh-Eteghad, S., Stannard, S. R., Earnest, C. P., Ramsbottom, R., Antonio, J., & Navin, K. H. (2020). Effects of Physical Activity on Brain Energy Biomarkers in Alzheimer's Diseases. Diseases (Basel, Switzerland), 8(2), 18. https://doi.org/10.3390/diseases8020018 van de Lagemaat, E. E., de Groot, L., & van den Heuvel, E. (2019). Vitamin B12in Relation to Oxidative Stress: A Systematic Review. Nutrients, 11(2), 482. https://doi.org/10.3390/nu11020482 Romain, M., Sviri, S., Linton, D. M., Stav, I., & van Heerden, P. V. (2016). The role of Vitamin B12 in the critically ill--a review. Anaesthesia and intensive care, 44(4), 447–452. https://doi.org/10.1177/0310057X1604400410 Shipton, M. J., & Thachil, J. (2015). Vitamin B12 deficiency - A 21st century perspective. Clinical medicine (London, England), 15(2), 145–150. https://doi.org/10.7861/clinmedicine.15-2-145 De Felice, M., Renard, J., Hudson, R., Szkudlarek, H. J., Pereira, B. J., Schmid, S., Rushlow, W. J., & Laviolette, S. R. (2021). l-Theanine Prevents Long-Term Affective and Cognitive Side Effects of Adolescent Δ-9-Tetrahydrocannabinol Exposure and Blocks Associated Molecular and Neuronal Abnormalities in the Mesocorticolimbic Circuitry. The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(4), 739–750. https://doi.org/10.1523/JNEUROSCI.1050-20.2020 De Felice, M., Renard, J., Hudson, R., Szkudlarek, H. J., Pereira, B. J., Schmid, S., Rushlow, W. J., & Laviolette, S. R. (2021). l-Theanine Prevents Long-Term Affective and Cognitive Side Effects of Adolescent Δ-9-Tetrahydrocannabinol Exposure and Blocks Associated Molecular and Neuronal Abnormalities in the Mesocorticolimbic Circuitry. The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(4), 739–750. https://doi.org/10.1523/JNEUROSCI.1050-20.2020 Nemetchek, M. D., Stierle, A. A., Stierle, D. B., & Lurie, D. I. (2017). The Ayurvedic plant Bacopa monnieri inhibits inflammatory pathways in the brain. Journal of ethnopharmacology, 197, 92–100. https://doi.org/10.1016/j.jep.2016.07.073 Kongkeaw, C., Dilokthornsakul, P., Thanarangsarit, P., Limpeanchob, N., & Norman Scholfield, C. (2014). Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract. Journal of ethnopharmacology, 151(1), 528–535. https://doi.org/10.1016/j.jep.2013.11.008 Sukumaran, N. P., Amalraj, A., & Gopi, S. (2019). Neuropharmacological and cognitive effects of Bacopa monnieri (L.) Wettst - A review on its mechanistic aspects. Complementary therapies in medicine, 44, 68–82. https://doi.org/10.1016/j.ctim.2019.03.016 Lurie DI CJ. The role of bacopa monnieri in inflammatory and neurodegenerative diseases. In: Motohashi N, editor. Occurrences, Structure, Biosynthesis, and Health Benefits Based on Their Evidences of Medicinal Phytochemicals in Vegetables and Fruits.Nova Science Publishers; New York, USA: 2015a. pp. 27–61. [Google Scholar] Hoffer, L. J., Sher, K., Saboohi, F., Bernier, P., MacNamara, E. M., & Rinzler, D. (2003). N-acetyl-L-tyrosine as a tyrosine source in adult parenteral nutrition. JPEN. Journal of parenteral and enteral nutrition, 27(6), 419–422. https://doi.org/10.1177/0148607103027006419 Velazquez, R., Ferreira, E., Knowles, S., Fux, C., Rodin, A., Winslow, W., & Oddo, S. (2019). Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation. Aging cell, 18(6), e13037. https://doi.org/10.1111/acel.13037 63 Jadavji, N. M., Emmerson, J. T., MacFarlane, A. J., Willmore, W. G., & Smith, P. D. (2017). B-vitamin and choline supplementation increases neuroplasticity and recovery after stroke. Neurobiology of disease, 103, 89–100. https://doi.org/10.1016/j.nbd.2017.04.001 Jacobson, S. W., Carter, R. C., Molteno, C. D., Stanton, M. E., Herbert, J. S., Lindinger, N. M., Lewis, C. E., Dodge, N. C., Hoyme, H. E., Zeisel, S. H., Meintjes, E. M., Duggan, C. P., & Jacobson, J. L. (2018). Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Alcoholism, clinical and experimental research, 42(7), 1327–1341. https://doi.org/10.1111/acer.13769 Bailey, L. B., Stover, P. J., McNulty, H., Fenech, M. F., Gregory, J. F., 3rd, Mills, J. L., Pfeiffer, C. M., Fazili, Z., Zhang, M., Ueland, P. M., Molloy, A. M., Caudill, M. A., Shane, B., Berry, R. J., Bailey, R. L., Hausman, D. B., Raghavan, R., & Raiten, D. J. (2015). Biomarkers of Nutrition for Development-Folate Review. The Journal of nutrition, 145(7), 1636S–1680S. https://doi.org/10.3945/jn.114.206599 * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$34.99
GENESIS BCAA (FRUIT PUNCH)
BCAA stands for Branched-chain amino acids: which prevent fatigue and improve concentration, reduce protein and muscle breakdown during and after an intense exercise. Genesis BCAA Post Workout after an intense workout has been shown to aid in maintaining muscle growth and energy required to reduce muscle breakdown. Containing: L-Glutamine for enhanced exercise performance, L-leucine for stimulated muscle growth, Vitamin B6 for energy and L-Valine for promoted muscle growth and tissue support. Flavor: Tropical Punch Serving Size: 6.5 Grams Servings Per Container: 45 Bottle Size: 292 Grams Formula Purposes & Benefits Genesis Blends BCAA Shock is synthesized to improve exercise performance, increase muscle protein synthesis, prevent muscle tissue breakdown, support immunity, gut health, and recovery. Our product is synthesized utilizing the latest scientific research and formulated with optimal ratios of branch chain amino acids to produce world-class results. Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Vitamin B6 pyridoxal 5'-phosphate (PLP) ● Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). ● Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). ● Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). ● May support blood sugar regulation in women with gestational diabetes (40). ● Cofactor for enzymes involved in DNA metabolism (40). BCAA 2:1 Ratio ● Improve exercise performance, increase muscle protein synthesis, prevent muscle tissue breakdown, supports immunity, gut health, lipid metabolism, and recovery (41,42). ● Leucine stimulates muscle protein synthesis (muscle growth) via stimulation of the mTORC1 pathway (a genetic pathway for cell growth) even in a caloric deficit (41). ● Suppresses muscle degradative pathway (muscle tissue break down) during times of catabolism and caloric deficit (41). ● Leucine stimulates muscle growth in sarcopenic elderly individuals that have increased leucine needs (41). ● Acts as a regulator to promote intestinal development, nutrient transporters, and immune-related function (42). L-Glutamine ● Most abundant amino acid in skeletal muscle that fuels immune cells, improves exercise recovery, and optimizes gut microbiome (18). ● Vital for lymphocyte (immune cell) proliferation (growth) and paramount in neutrophil (immune cell) destruction of bacteria (18). ● Vital for activation of genetic signals that support immune function and vitality (18). ● Glutamine is utilized by immune cells at high rates during catabolic conditions (post-surgery, sepsis, burns, and extreme exercise (18). Proper Use of This Supplement Suggested Use: As a dietary supplement Mix 1/2 a scoop (6.5g) in 8 - 10 ounces of cold beverage. It will take a few minutes for all the powder to dissolve in the beverage. Best taken pre-workout, post-workout or between meals Our Formula Vs Other Formulas on the Market. 1. Uses third party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third party tested have been removed by FDA due to high levels of heavy metals. 2. Utilizes efficacious evidence-based dosages with optimal ratios of amino acids to support exercise performance and recovery. 2. Use low amounts of cheap forms of amino acids that result in poor absorption and muscle growth, recovery, and exercise performance. Sources: Cruzat, V., Macedo Rogero, M., Noel Keane, K., Curi, R., & Newsholme, P. (2018). Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Nutrients, 10(11), 1564. https://doi.org/10.3390/nu10111564 Ueland, P. M., McCann, A., Midttun, Ø., & Ulvik, A. (2017). Inflammation, vitamin B6 and related pathways. Molecular aspects of medicine, 53, 10–27. https://doi.org/10.1016/j.mam.2016.08.001 Bird R. P. (2018). The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis. Advances in food and nutrition research, 83, 151–194. https://doi.org/10.1016/bs.afnr.2017.11.004 Mascolo, E., & Vernì, F. (2020). Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms. International journal of molecular sciences, 21(10), 3669. https://doi.org/10.3390/ijms21103669 Nie, C., He, T., Zhang, W., Zhang, G., & Ma, X. (2018). Branched Chain Amino Acids: Beyond Nutrition Metabolism. International journal of molecular sciences, 19(4), 954. https://doi.org/10.3390/ijms19040954 Fan, P., Li, L., Rezaei, A., Eslamfam, S., Che, D., & Ma, X. (2015). Metabolites of Dietary Protein and Peptides by Intestinal Microbes and their Impacts on Gut. Current protein & peptide science, 16(7), 646–654. https://doi.org/10.2174/1389203716666150630133657 * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$29.99
GENESIS CBD GUMMIES - BROAD SPECTRUM
CBD Edibles have become extremely popular over the last couple of years due to their wide range of benefits and positive effects they have on the body. Genesis Blends CBD Isolate coated Gummies are an extremely tasty way to take your daily dose of CBD. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$34.99
GENESIS CBD OIL - 500 MG BROAD SPECTRUM
Premium quality tincture procured from organically grown crops in Colorado. Non-GMO, pesticide, herbicide, solvent and chemical free and lab tested to ensure potency. Our CBD tinctures are high quality, fast acting way to get the active ingredients quickly into the body. The key differences between CBD oils and CBD capsules is the mode in which they're broken down by the body. CBD oils offer slightly more potency and longer-lasting effects, given that they're taken under the tongue and are absorbed directly into the bloodstream via tiny sublingual capillary beds. Because of this, oil drops are not subject to metabolic breakdown, and therefore more of the active CBD is available to reach the target destination and provide its therapeutic effects. The 500 mg tincture is a perfect monthly amount of CBD for a person requiring a higher concentrated dose of the CBD for more than just noticeable pain or symptoms. Serving Size: 1 ml Servings Per Bottle: 30 * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$39.99
GENESIS CBD MUSCLE CREAM - 10 MG BROAD SPECTRUM
A perfect blend of high quality Broad Spectrum CBD Oil and Menthol formulated to ease discomfort by targeting specific areas of the body as a topical solution. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$29.99
GENESIS CALMING FORMULA
In today's crazy world finding calm and relaxation can be very difficult. Our Deep Calm supplement contains ingredients like chamomile, lemon balm and ashwagandha, commonly known for their relaxing qualities. Serving Size: 2 Capsules Servings Per Container: 30 Formula Purposes & Benefits Genesis Blends Calming Formula is formulated to support reduced anxiety, healthy sleep cycles (circadian rhythm), relaxation, reduce mental fatigue and improve mood. Our product is synthesized utilizing the latest scientific research and formulated with high quality ingredients. Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards. Formula Ingredient Deck Benefits Of Each Ingredient Calcium Carbonate ● Supports bone health, muscle function, and cardiovascular health (36,37). ● Regulates processes of bone resorption, mineralization, and fracture repair (36,37). ● Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37). ● Prevents the development of preeclampsia (36,37). Vitamin B1 ● Supports aerobic energy metabolism (oxidative phosphorylation), cell growth, optimal neuronal conduction (nerve impulses), and cardiovascular health (94). ● Supports cardiovascular function and aids as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95). Vitamin B2 ● Supports conversion and activation of other B vitamins, red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93). Vitamin B5 ● Supports energy production, cell growth, cell repair, cognitive function, increased hippocampal volume (memory), and optimized bioenergetics (burning of carbohydrates, fat, and protein) (96). Vitamin B6 ● Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). ● Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). ● Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). ● May support blood sugar regulation in women with gestational diabetes (40). ● Cofactor for enzymes involved in DNA metabolism (40). Vitamin B3 (Niacin) ● Major B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9). ● Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9). ● Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9). ● Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9). ● Prevents pathologies(diseases) such as Pellagra and reduces prevalence of nervous anorexia, cancer, and crohn's disease (10, 11). ● Supports sensitization of tumors to radiation via apoptosis (cell death) cascade of tumor mass and improves oxygen delivery to malignant tissues (cancer cells) (12). ● Supports cognitive health by reducing age-related decline of NAD+, increasing quinolinic acid and reducing neuroinflammation (9). ● Increased niacin associated NAD+ levels have been shown to increase neurotransmission, learning and memory (9). ● Niacin reduces the prevalence of neurodegenerative pathologies by preventing mitochondrial dysfunction (9). Biotin ● Supports conversion of food into cellular energy, hair health, skin health, and cognitive function (213,214). ● Enhances glucose breakdown into skeletal muscle tissue (213,214). Potassium ● Supports reduced blood pressure in hypertensive patients and improves hydration in individuals with low potassium levels (262). Magnesium ● Supports optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91). ● Supports biological reactions such as ATP fueled reactions and pancreatic insulin secretion (90,91). ● Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91). ● Reduces peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91). Zinc ● Supports immune function, skin health, cognitive function, and vision (172,173). ● Supports stimulation of the innate and adaptive immune system (172,173). ● Supports the activation of lymphocytes and activation of innate and T cell mediated immunity (172,173). ● Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173). Rhodiola Lutein ● Carotenoid that supports vision health, immune health, cardiovascular health, and combats diabetic retinopathy (155,156). ● Supports increased lutein concentration in the macula and exhibits various features such as anti-inflammatory, anti-oxidative, and blue light-filtering effects (155,156). ● Supports visual health via increased lutein concentration in the macular layer of retina, reduced susceptibility to age related macular disease, reduced prevalence of cataracts, and improved plasma level of lutein and retinal macular pigment level (155,156). Chamomile ● Supports healthy sleep, relaxation, reduced anxiety, and antioxidant support (251,252,253). ● Supports antioxidant function due to high levels of quercetin (flavonoid antioxidant) (251,252,253). ● Supports sleep via increases in parasympathetic (relaxation mode) activity, increased benzodiazepine-like hypnotic activity (sleep inducer), and attachment to GABA receptors (251,252,253). Lemon Balm ● Supports healthy sleep, relaxation, reduced anxiety, and antioxidant support (254,255). ● Supports antioxidant function via ability to scavenge free radicals, reduce oxidative stress, increased glutathione production (master antioxidant) combat DNA damage (254,225). ● Supports relaxed sleep via enhanced REM cycles reduced stress at bedtime (254,225). Passion Flower ● Reduces stress, enhances sleep, and improved mood (248) ● Enhances positive mood and sleep via regulated gamma‐aminobutyric acid receptor A (GABAA) activity (receptor which controls sleep) (248). Hawthorn Berry ● Supports cardiovascular health and combats metabolic syndrome (165). ● Supports cardiovascular health via reduced atherosclerotic lesion areas, reduced cholesterol synthesis (acyl-coA-cholesterol acyltransferase enzyme), reduced very low-density lipoproteins (VLDL), and inhibited platelet aggregation (165). Munica Pruriens ● Supports blood sugar regulation, sexual enhancement, aids an anti-inflammatory agent, combats neurodegenerative disease, and supports antimicrobial activity (128). ● Supports anti-aging, rheumatoid, arthritis, diabetes, male infertility, and nervous disorders (128). ● Supports male sexual health via increased sperm motility and increased free testosterone (128). ● Combats neurodegenerative disease via stimulation of dopaminergic neurons (129). ● Supports blood sugar health via reduced blood glucose levels, improved insulin transport, and lowered H1AC levels (130). St. John’s Wort ● Combats depression and supports positive mood (249,250). GABA ● Supports relaxation, positive mood, increased memory, reduced anxiety, blood sugar regulation, and increased growth hormone production (102). Skullcap ● Supports calming mood and relaxation. L-Theanine ● Unique non-protein amino acid found in green tea (Camellia sinensis) (53). ● Supports mood, mental clarity, and cognitive health, memory, and is a natural anti-depressant/neuroprotective agent (53). ● Aids as an antidepressant due to partial antagonism for the N-methyl-D-aspartate receptor manifesting its cognitive optimizing effects (53). ● Reduces the neuropsychiatric side effects of chronic adolescent THC exposure (54). Ashwagandha ● Supports cardiovascular, hormonal, immune, healthy weight loss, mood, and optimized sleep (82,83). ● Reduces stress hormone cortisol resulting in improved body composition, sex hormone profile, and mood (82,83). ● Improves exercise performance via increased V02 max, muscular endurance, muscle hypertrophy (muscle growth), and decreased muscular fatigue (83). ● Improves quality of sleep by enhancing sleep recovery, reducing plasma cortisol concentrations, and enhancing REM sleep cycles (83). ● Supports hormonal and immune health via reduced production of inflammatory molecules (reactive oxygen species) and simultaneous increases in sex hormones (84). Bacopa ● Supports cognitive function, memory, alertness, and aids as an anti-stress agent (57). ● May combat inflammatory conditions such as asthma, bronchitis, dropsy, and rheumatism (56,59). ● Bacopa has been shown to have anti-inflammatory effects on macrophages (immune cells) and inhibits the release of IL-6 and TNF-α (inflammatory markers) from monocytes (immune cells) (58,59,). ● Promising candidate for the development of novel therapeutics that target neuroinflammation and have the potential for treating a wide range of CNS disorders including Alzheimer's disease, depression, and schizophrenia (59). Magnolia ● Supports antioxidant function, positive mood, and aids a neuroprotective agent (263,264). ● Supports relaxed shorten sleep latency and regulated gamma‐aminobutyric acid receptor A (GABAA) activity (receptor which controls sleep) (263,264). Griffonia Seed Ext -5-HTP ● Supports healthy sleep patterns, mood, reduced anxiety, and supports the gut brain axis (261). ● Supports healthy sleep patterns via enhanced circadian rhythm and increased natural melatonin production (261). ● Supports gut brain axis via natural increased production of serotonin (neurotransmitter) in gut neurons (260, 261). Valarian Root ● Reduces stress, enhances sleep, and improved mood (244,245). ● Enhances positive mood and sleep via regulated gamma‐aminobutyric acid receptor A (GABAA) activity (receptor which controls sleep) (244, 245). Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules twice a day. For best results, take 20-30 minutes before a meal with an 8 oz glass of water, or as directed by your health care professional. Our Formula Vs Other Formulas on the Market. 1. Uses third party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third party tested have been removed by FDA due to high levels of heavy metals. 2. Uses high quality nutraceuticals in an effective evidence based and efficaciously dosed formula. 2. Uses cheap sources of nutraceuticals that contain high amounts of fillers, heavy metals, and in formulated without evidence based dosages. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$25.99
GENESIS DRIVE FOR WOMEN
A blend of natural herbs and vitamins that are specifically formulated to naturally help enhance female libido levels, stamina, sexual stimulation, and enjoyment, by helping the body increase natural lubrication, for a more heighten sexual response. Serving Size: 2 Capsules Servings Per Container: 30 Formula Purposes & Benefits Genesis Blends Drive For Women is formulated to increase sexual arousal, sexual function, positive mood, reduced cortisol, increased nitric oxide production, increased muscle mass, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high-quality ingredients. Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Vitamin A (beta carotene) ● Supports vision health, skin health, immune health, and increases antioxidant support (182, 183). ● Supports antioxidant function via decreased inflammatory cytokines (inflammation), decreased reactive oxygen species, and increased l-glutathione production (master antioxidant) (182, 183). ● Supports visual health via increased amounts of plasma vitamin A in macular (eye) tissues (182, 183). Vitamin B1 (Thiamine) ● Supports aerobic energy metabolism (oxidative phosphorylation), cell growth, optimal neuronal conduction (nerve impulses), and cardiovascular health (94). ● Supports cardiovascular function and aids as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95). Vitamin B2 (Riboflavin) ● Supports conversion and activation of other B vitamins, red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93). Vitamin B3 (Niacin) ● Major B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9). ● Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9). ● Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9). ● Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9). ● Prevents pathologies(diseases) such as Pellagra and reduces prevalence of nervous anorexia, cancer, and crohn's disease (10, 11). ● Supports sensitization of tumors to radiation via apoptosis (cell death) cascade of tumor mass and improves oxygen delivery to malignant tissues (cancer cells) (12). ● Supports cognitive health by reducing age-related decline of NAD+, increasing quinolinic acid and reducing neuroinflammation (9). ● Increased niacin associated NAD+ levels have been shown to increase neurotransmission, learning and memory (9). ● Niacin reduces the prevalence of neurodegenerative pathologies by preventing mitochondrial dysfunction (9). Vitamin B6 ● Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). ● Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). ● Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). ● May support blood sugar regulation in women with gestational diabetes (40). ● cofactor for enzymes involved in DNA metabolism (40). Vitamin B12 ● Supports proper DNA synthesis, folate cycle function, energy production, cognitive function, and immune health (51,53). ● Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress (51). ● May prevent vitamin b-12 deficiency diseases such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis (53). Zinc ● Supports immune function, skin health, cognitive function, and vision (172,173). ● Supports stimulation of the innate and adaptive immune system (172,173). ● Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173). ● Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173). L-Tyrosine ● Supports memory, cognitive flexibility, the executive function of the brain, and convergent thinking (60). ● A precursor to dopamine and is vital for dopamine synthesis in the brain (60). ● Supports cognitive function in individuals with high amounts of stress and anxiety (60,61). ● Increases dopamine levels in highly stressed individuals (60). Maca Root Powder ● Supports female hormonal health via increased sex drive, improved post-menopausal symptoms, and improved sexual desire (13). ● Increases luteinizing hormone (LH) production and reduced severity of menstruation (13). ● Increases sperm count in males via androgenic mechanisms associated with free testosterone increase (13). Munica Pruriens ● Supports blood sugar regulation, sexual enhancement, aids an anti-inflammatory agent, combats neurodegenerative disease, and supports antimicrobial activity (128). ● Supports anti-aging, rheumatoid, arthritis, diabetes, male infertility, and nervous disorders (128). ● Supports male sexual health via increased sperm motility and increased free testosterone (128). ● Combats neurodegenerative disease via stimulation of dopaminergic neurons (129). ● Supports blood sugar health via reduced blood glucose levels, improved insulin transport, and lowered H1AC levels (130). Muira Puama Root Powder ● Supports sexual vitality in males and females, reduces stress, and increases blood flow to sexual organs (135). L-Arginine ● Natural vasodilator precursor to increased nitric oxide levels (1). ● Supports immune function by the maturation of the T cell (immune cell) receptor zeta (TCR) (2.) ● Improves exercise performance via increased stroke volume (blood flow) and increased nutrient delivery to exercising muscle. (3). ● Reduces arterial blood pressure, insulin resistance, and supports fat lipolysis (fat burning) (4). Panax Ginseng ● An adaptogenic herb that supports antioxidant function, cognitive function, increased muscle mass, combats inflammation, stabilizes blood pressure, enhances sexual health, and enhances endurance performance (136). ● Combats inflammation via inhibition of hydroxyl radical(inflammation) and lipid peroxidation (136). ● Supports endurance performance by enhancing mitochondrial energy output during exercise (136). Epimedium/Horny Goat Weed ● Supports increased sexual drive, increased testosterone, reduced progression of atherosclerosis, increased nitric oxide levels, and reduced arterial (blood vessel) inflammation levels (126,127). ● Reduces arterial inflammation via reduction of free-radical-induced peroxidation in erythrocytes, and increased nitric oxide levels (126,127). ● Supports arterial health (health of blood vessels) via attenuating DNA damage, correcting endothelial dysfunction (126,127). ● Represses macrophage-derived foam cell formation, inhibiting platelet activation, and reduces oxLDL-induced monocyte adhesion to endothelial cells (126,127). Dong Quai ● Supports menstrual health in women. Tribulus Terrestris ● Supports sexual function, increased testosterone, cardiovascular health, supports healthy urinary tract function, supports athletic performance, and aids as a neuroprotective agent (137,138). ● Supports sexual health, via activating aphrodisiacs, increased spermatogenesis, sperm motility, increased free testosterone, and increase of androgenic (hormone) action via the activation of endogenous testosterone production (137,138). ● Supports cardiovascular health via decreased arterial inflammation levels of tumor necrosis factor (TNF)-α and interleukin (IL)-6 (137,138). ● Supports neuroprotective properties via protection of neuron injury, and cerebral ischemia-reperfusion by suppressing brain inflammatory markers (NF-κB, TNF-α and IL-1β) (137,138). Damiana ● Supports enhanced sexual function, reduced menopausal symptoms, reduced stress, and improved mood (139). ● Supports sexual health via regulation of the natural balance between androgens and estrogens in both men and women (139). Ashwagandha ● Supports cardiovascular, hormonal, immune, healthy weight loss, mood, and optimized sleep (82,83). ● Reduces stress hormone cortisol resulting in improved body composition, sex hormone profile, and mood (82,83). ● Improves exercise performance via increased V02 max, muscular endurance, muscle hypertrophy (muscle growth), and decreased muscular fatigue (83). ● Improves quality of sleep by enhancing sleep recovery, reducing plasma cortisol concentrations, and enhancing REM sleep cycles (83). ● Supports hormonal and immune health via reduced production of inflammatory molecules (reactive oxygen species) and simultaneous increases in sex hormones (84). Ginger ● Supports immune health, reduced blood pressure, digestive health, blood sugar regulation, and sexual health in men (110). ● Supports immune health via enhanced antioxidant, antimicrobial, and anti-inflammatory properties (110). ● Supports sex hormone health via decreased oxidative stress, increased luteinizing hormone (LH) production, reduced oxidative stress, reduced lipid peroxidation, enhanced activity antioxidant enzymes, increased blood flow, and recycling of testosterone receptors (110). Sarsaparilla root ● Supports Antioxidant activity, antimicrobial activity, immune system activity, and skin health (140). ● Supports skin health by inhibiting oxidative damage and skin-aging factor via mitogen-activated protein kinase signaling pathways (141). ● Supports immune health and antioxidant activity by increasing l-glutathione levels (master antioxidant) and enhanced free radical scavenging capabilities (141). Asparagus ● Supports immune health, enhances cognitive function, and combats neurodegenerative disease Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules once a day. For best results, light exercise and a sensible diet are recommended. Use this product for no less than 8 weeks for maximum results. Do not exceed 4 capsules a day. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. High-quality turmeric and ginger in an effective and efficaciously dosed formula 2. Uses cheap sources of turmeric and ginger that contain high amounts of fillers and heavy metals. Sources 1.Sureda, A., & Pons, A. (2012). Arginine and citrulline supplementation in sports and exercise: ergogenic nutrients?. Medicine and sport science, 59, 18–28. https://doi.org/10.1159/000341937 2.Szefel, J., Danielak, A., & Kruszewski, W. J. (2019). Metabolic pathways of L-arginine and therapeutic consequences in tumors. Advances in medical sciences, 64(1), 104–110. https://doi.org/10.1016/j.advms.2018.08.018 3.Rodrigues-Krause, J., Krause, M., Rocha, I., Umpierre, D., & Fayh, A. (2018). Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis. Nutrients, 11(1), 15. https://doi.org/10.3390/nu11010015 4.Hu, S., Han, M., Rezaei, A., Li, D., Wu, G., & Ma, X. (2017). L-Arginine Modulates Glucose and Lipid Metabolism in Obesity and Diabetes. Current protein & peptide science, 18(6), 599–608. https://doi.org/10.2174/1389203717666160627074017 9.Gasperi, V., Sibilano, M., Savini, I., & Catani, M. V. (2019). Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications. International journal of molecular sciences, 20(4), 974. https://doi.org/10.3390/ijms20040974 10.Gentilcore D. (2016). Louis Sambon and the Clash of Pellagra Etiologies in Italy and the United States, 1905-14. Journal of the history of medicine and allied sciences, 71(1), 19–42. https://doi.org/10.1093/jhmas/jrv002 11.Kirkland J. B. (2009). Niacin status and treatment-related leukemogenesis. Molecular cancer therapeutics, 8(4), 725–732. https://doi.org/10.1158/1535-7163.MCT-09-0042 12.Hoskin, P., Rojas, A., & Saunders, M. (2009). Accelerated radiotherapy, carbogen, and nicotinamide (ARCON) in the treatment of advanced bladder cancer: mature results of a Phase II nonrandomized study. International journal of radiation oncology, biology, physics, 73(5), 1425–1431. https://doi.org/10.1016/j.ijrobp.2008.06.1950 Ueland, P. M., McCann, A., Midttun, Ø., & Ulvik, A. (2017). Inflammation, vitamin B6 and related pathways. Molecular aspects of medicine, 53, 10–27. https://doi.org/10.1016/j.mam.2016.08.001 Bird R. P. (2018). The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis. Advances in food and nutrition research, 83, 151–194. https://doi.org/10.1016/bs.afnr.2017.11.004 Mascolo, E., & Vernì, F. (2020). Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms. International journal of molecular sciences, 21(10), 3669. https://doi.org/10.3390/ijms21103669 van de Lagemaat, E. E., de Groot, L., & van den Heuvel, E. (2019). Vitamin B12in Relation to Oxidative Stress: A Systematic Review. Nutrients, 11(2), 482. https://doi.org/10.3390/nu11020482 Romain, M., Sviri, S., Linton, D. M., Stav, I., & van Heerden, P. V. (2016). The role of Vitamin B12 in the critically ill--a review. Anaesthesia and intensive care, 44(4), 447–452. https://doi.org/10.1177/0310057X1604400410 Shipton, M. J., & Thachil, J. (2015). Vitamin B12 deficiency - A 21st century perspective . Clinical medicine (London, England), 15(2), 145–150. https://doi.org/10.7861/clinmedicine.15-2-145 Hoffer, L. J., Sher, K., Saboohi, F., Bernier, P., MacNamara, E. M., & Rinzler, D. (2003). N-acetyl-L-tyrosine as a tyrosine source in adult parenteral nutrition. JPEN. Journal of parenteral and enteral nutrition, 27(6), 419–422. https://doi.org/10.1177/0148607103027006419 Ipson, B. R., & Fisher, A. L. (2016). Roles of the tyrosine isomers meta-tyrosine and ortho-tyrosine in oxidative stress. Ageing research reviews, 27, 93–107. https://doi.org/10.1016/j.arr.2016.03.005 Langade, D., Kanchi, S., Salve, J., Debnath, K., & Ambegaokar, D. (2019). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus, 11(9), e5797. https://doi.org/10.7759/cureus.5797 Bonilla, D. A., Moreno, Y., Gho, C., Petro, J. L., Odriozola-Martínez, A., & Kreider, R. B. (2021). Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis. Journal of functional morphology and kinesiology, 6(1), 20. https://doi.org/10.3390/jfmk6010020 Thakur, K., Tomar, S. K., Singh, A. K., Mandal, S., & Arora, S. (2017). Riboflavin and health: A review of recent human research. Critical reviews in food science and nutrition, 57(17), 3650–3660. https://doi.org/10.1080/10408398.2016.1145104 Suwannasom, N., Kao, I., Pruß, A., Georgieva, R., & Bäumler, H. (2020). Riboflavin: The Health Benefits of a Forgotten Natural Vitamin. International journal of molecular sciences, 21(3), 950. https://doi.org/10.3390/ijms21030950 DiNicolantonio, J. J., Niazi, A. K., Lavie, C. J., O'Keefe, J. H., & Ventura, H. O. (2013). Thiamine supplementation for the treatment of heart failure: a review of the literature. Congestive heart failure (Greenwich, Conn.), 19(4), 214–222. https://doi.org/10.1111/chf.12037 Saedisomeolia, A., & Ashoori, M. (2018).Thiamine in Human Health: A Review of Current Evidences. Advances in food and nutrition research, 83, 57–81. https://doi.org/10.1016/bs.afnr.2017.11.002 Hasani, H., Arab, A., Hadi, A., Pourmasoumi, M., Ghavami, A., & Miraghajani, M. (2019). Does ginger supplementation lower blood pressure? A systematic review and meta-analysis of clinical trials. Phytotherapy research : PTR, 33(6), 1639–1647. https://doi.org/10.1002/ptr.6362 Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.00734 13.Dording, C. M., Schettler, P. J., Dalton, E. D., Parkin, S. R., Walker, R. S., Fehling, K. B., Fava, M., & Mischoulon, D. (2015). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evidence-based complementary and alternative medicine : eCAM, 2015, 949036. https://doi.org/10.1155/2015/949036 Pathania, R., Chawla, P., Khan, H., Kaushik, R., & Khan, M. A. (2020). An assessment of potential nutritive and medicinal properties of Mucuna pruriens: a natural food legume. 3 Biotech, 10(6), 261. https://doi.org/10.1007/s13205-020-02253-x Rakesh B, Praveen N (2020) Chapter-10 biotechnological approaches for the production of l-DOPA: a novel and potent anti-Parkinson’s Drug from Mucuna pruriens (L.) DC. Chief Editor: 179 Majekodunmi, S. O., Oyagbemi, A. A., Umukoro, S., & Odeku, O. A. (2011). Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract. Asian Pacific journal of tropical medicine, 4(8), 632–636. https://doi.org/10.1016/S1995-7645(11)60161-2 Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells. Nitric oxide : biology and chemistry, 76, 81–86. https://doi.org/10.1016/j.niox.2018.03.010 Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Saudan, C., Baume, N., Emery, C., Strahm, E., & Saugy, M. (2008). Short term impact of Tribulus terrestris intake on doping control analysis of endogenous steroids. Forensic science international, 178(1), e7–e10. https://doi.org/10.1016/j.forsciint.2008.01.003 Palacios, S., Soler, E., Ramírez, M., Lilue, M., Khorsandi, D., & Losa, F. (2019). Effect of a multi-ingredient based food supplement on sexual function in women with low sexual desire. BMC women's health, 19(1), 58. https://doi.org/10.1186/s12905-019-0755-9 Das, S., & Bisht, S. S. (2013). The bioactive and therapeutic potential of Hemidesmus indicus R. Br. (Indian Sarsaparilla) root. Phytotherapy research : PTR, 27(6), 791–801. https://doi.org/10.1002/ptr.4788 She, T., Qu, L., Wang, L., Yang, X., Xu, S., Feng, J., Gao, Y., Zhao, C., Han, Y., Cai, S., & Shou, C. (2015). Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy via Redox-Dependent ERK1/2 Pathway. Cancer prevention research (Philadelphia, Pa.), 8(5), 464–474. https://doi.org/10.1158/1940-6207.CAPR-14-0372 Majumdar, S., Gupta, S., Prajapati, S. K., & Krishnamurthy, S. (2021). Neuro-nutraceutical potential of Asparagus racemosus: A review. Neurochemistry international, 145, 105013. https://doi.org/10.1016/j.neuint.2021.105013 Maywald, M., Wessels, I., & Rink, L. (2017). Zinc Signals and Immunity. International journal of molecular sciences, 18(10), 2222. https://doi.org/10.3390/ijms18102222 Wessels, I., Rolles, B., & Rink, L. (2020). The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis. Frontiers in immunology, 11, 1712. https://doi.org/10.3389/fimmu.2020.01712 * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$29.99
GENESIS MALE ENHANCEMENT FORMULA
Genesis Male Enhancement Formula provides a blend of ingredients that may help to support stamina and sexual libido. Some of the main ingredients in this supplement are: Tongkat Ali, L-Arginine, vitamin b12, and bioperine. Serving Size: 2 Capsules Capsules Per Container: 60 Formula Purposes & Benefits Genesis Blends Male Enhancement Supplement is formulated to increase natural testosterone levels, positive mood, reduced cortisol, increased nitric oxide production, increased muscle mass, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high quality Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards. Formula Ingredient Deck Benefits Of Each Ingredient Horny Goat Weed ● Supports increased sexual drive, increased testosterone, reduced progression of atherosclerosis, increased nitric oxide levels, and reduced arterial (blood vessel) inflammation levels (126,127). ● Reduces arterial inflammation via reduction of free-radical-induced peroxidation in erythrocytes, and increased nitric oxide levels (126,127). ● Supports arterial health (health of blood vessels) via attenuating DNA damage, correcting endothelial dysfunction (126,127). ● represses macrophage-derived foam cell formation, inhibiting platelet activation, and reduces oxLDL-induced monocyte adhesion to endothelial cells (126,127). Macca Root Powder ● Supports female hormonal health via increased sex drive, improved post-menopausal symptoms, and improved sexual desire (13). ● Increases luteinizing hormone (LH) production and reduced severity of menstruation (13). ● Increases sperm count in males via androgenic mechanisms associated with free testosterone increase (13). Tongkat Ali ● Reduces stress hormones (cortisol), increases free testosterone, enhances mood, and supports sexual function (132). Saw Palmetto ● Supports prostate health, cardiovascular health, and increased hair growth (133,134). ● Supports prostate health via anti-androgenic and anti-inflammatory effects resulting in reduced Benign prostatic hyperplasia (134). L-Arginine ● Natural vasodilator precursor to increased nitric oxide levels (1). ● Supports immune function by maturation of the T cell (immune cell) receptor zeta (TCR) (2). ● Improves exercise performance via increased stroke volume (blood flow) and increased nutrient delivery to exercising muscle (3). ● Reduces arterial blood pressure, insulin resistance, and supports fat lipolysis (fat burning) (4). Panax Ginseng ● Apoptogenic herb that supports antioxidant function, cognitive function, increased muscle mass, combats inflammation, stabilizes blood pressure, enhances sexual health, and enhances endurance performance (136). ● Combats inflammation via inhibition of hydroxyl radical(inflammation) and lipid peroxidation (136). ● Supports endurance performance by enhancing mitochondrial energy output during exercise (136). Sarsaparilla Root ● Supports Antioxidant activity, antimicrobial activity, immune system activity, and skin health (140). ● Supports skin health by inhibiting oxidative damage and skin-aging factor via mitogen-activated protein kinase signaling pathways (141). ● Supports immune health and antioxidant activity by increasing l-glutathione levels (master antioxidant) and enhanced free radical scavenging capabilities (141). Pumpkin Seed Extract ● Supports urinary health, and immune function (175). ● Substantial improvement in BPH/LUTS. The observed symptom relief is accompanied by a clinically significant improvement in IPSS-related (175). Muira Puma Extract ● Supports sexual vitality in males and females, reduces stress, and increases blood flow to sexual organs (135). Oat Straw ● May support antioxidant function and cardiovascular health (185). Nettle ● Supports blood sugar regulation and urinary health. Cayenne Pepper ● Combats diarrhea, cramps, and muscle inflammation (176). ● Decreases muscle soreness and increases muscle strength (177). Astragalus Root ● Supports immune health, improves blood sugar regulation, and reduces inflammatory markers seen in gastrointestinal chronic diseases (16). ● Improves insulin resistance by reduction of inflammatory blood markers, increasing glucose uptake by exercising skeletal muscle, and improving glycogen (storage form of carbohydrates) synthesis (17). Catuba Bark ● May support antioxidant function. Licorice Root ● Supports anti-inflammatory, anti-allergenic, and antimicrobial properties (178). Tribulus Terrestris ● Supports sexual function, increased testosterone, cardiovascular health, supports healthy urinary tract function, supports athletic performance, and aids as a neuroprotective agent (137,138). ● Supports sexual health, via activating aphrodisiacs, increased spermatogenesis, sperm motility, increased free testosterone, and increase of androgenic (hormone) action via the activation of endogenous testosterone production (137,138). ● Supports cardiovascular health via decreased arterial inflammation levels of tumor necrosis factor (TNF)-α and interleukin (IL)-6 (137,138). ● Supports neuroprotective properties via protection of neuron injury, and cerebral ischemia-reperfusion by suppressing brain inflammatory markers (NF-κB, TNF-α and IL-1β) (137,138). Oyster Extract ● Reduces inflammation and supports joint health (178,179). ● Supports immune health via reduced generation of intracellular reactive oxygen species and increased levels of l-glutathione (master antioxidant) in macrophages (immune cells) (178,179). Boron ● Supports increased bone mineral density, muscle function, hormonal balance, and immune function (180). Proper Use of This Supplement Suggested Use: Take three (3) capsules before bedtime. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. Uses high-quality herbs, nootropics, vitamins, and minerals in an effective and efficaciously dosed formula. 2. Uses cheap sources of herbs, nootropics, vitamins, and minerals that contain high amounts of fillers and heavy metals. Sources 1.Sureda, A., & Pons, A. (2012). Arginine and citrulline supplementation in sports and exercise: ergogenic nutrients?. Medicine and sport science, 59, 18–28. https://doi.org/10.1159/000341937 2.Szefel, J., Danielak, A., & Kruszewski, W. J. (2019). Metabolic pathways of L-arginine and therapeutic consequences in tumors. Advances in medical sciences, 64(1), 104–110. https://doi.org/10.1016/j.advms.2018.08.018 3.Rodrigues-Krause, J., Krause, M., Rocha, I., Umpierre, D., & Fayh, A. (2018). Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis. Nutrients, 11(1), 15. https://doi.org/10.3390/nu11010015 4.Hu, S., Han, M., Rezaei, A., Li, D., Wu, G., & Ma, X. (2017). L-Arginine Modulates Glucose and Lipid Metabolism in Obesity and Diabetes. Current protein & peptide science, 18(6), 599–608. https://doi.org/10.2174/1389203717666160627074017 Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x 13.Dording, C. M., Schettler, P. J., Dalton, E. D., Parkin, S. R., Walker, R. S., Fehling, K. B., Fava, M., & Mischoulon, D. (2015). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evidence-based complementary and alternative medicine : eCAM, 2015, 949036. https://doi.org/10.1155/2015/949036 Auyeung, K. K., Han, Q. B., & Ko, J. K. (2016). Astragalus membranaceus: A Review of its Protection Against Inflammation and Gastrointestinal Cancers. The American journal of Chinese medicine, 44(1), 1–22. https://doi.org/10.1142/S0192415X16500014 Zhang, Z., Zhang, L., & Xu, H. (2019). Effect of Astragalus polysaccharide in treatment of diabetes mellitus: a narrative review. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 39(1), 133–138. Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.00734 Rehman, S. U., Choe, K., & Yoo, H. H. (2016). Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules (Basel, Switzerland), 21(3), 331. https://doi.org/10.3390/molecules21030331 Evron, E., Juhasz, M., Babadjouni, A., & Mesinkovska, N. A. (2020). Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia. Skin appendage disorders, 6(6), 329–337. https://doi.org/10.1159/000509905 Kwon Y. (2019). Use of saw palmetto (Serenoa repens) extract for benign prostatic hyperplasia. Food science and biotechnology, 28(6), 1599–1606. https://doi.org/10.1007/s10068-019-00605-9 Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells. Nitric oxide : biology and chemistry, 76, 81–86. https://doi.org/10.1016/j.niox.2018.03.010 Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Saudan, C., Baume, N., Emery, C., Strahm, E., & Saugy, M. (2008). Short term impact of Tribulus terrestris intake on doping control analysis of endogenous steroids. Forensic science international, 178(1), e7–e10. https://doi.org/10.1016/j.forsciint.2008.01.003 Das, S., & Bisht, S. S. (2013). The bioactive and therapeutic potential of Hemidesmus indicus R. Br. (Indian Sarsaparilla) root. Phytotherapy research : PTR, 27(6), 791–801. https://doi.org/10.1002/ptr.4788 She, T., Qu, L., Wang, L., Yang, X., Xu, S., Feng, J., Gao, Y., Zhao, C., Han, Y., Cai, S., & Shou, C. (2015). Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy via Redox-Dependent ERK1/2 Pathway. Cancer prevention research (Philadelphia, Pa.), 8(5), 464–474. https://doi.org/10.1158/1940-6207.CAPR-14-0372 Hsu, Y. J., Huang, W. C., Chiu, C. C., Liu, Y. L., Chiu, W. C., Chiu, C. H., Chiu, Y. S., & Huang, C. C. (2016). Capsaicin Supplementation Reduces Physical Fatigue and Improves Exercise Performance in Mice. Nutrients, 8(10), 648. https://doi.org/10.3390/nu8100648 Eichner E. R. (2016). Fighting Muscle Cramps With Two Spices and One Hot Fruit. Current sports medicine reports, 15(5), 304–305. https://doi.org/10.1249/JSR.0000000000000298 Lee, S. Y., Kim, H. J., & Han, J. S. (2013). Anti-inflammatory Effect of Oyster Shell Extract in LPS-stimulated Raw 264.7 Cells. Preventive nutrition and food science, 18(1), 23–29. https://doi.org/10.3746/pnf.2013.18.1.023 Jeong, J. W., Choi, S. H., Han, M. H., Kim, G. Y., Park, C., Hong, S. H., Lee, B. J., Park, E. K., Kim, S. O., Leem, S. H., Jeon, Y. J., & Choi, Y. H. (2019). Protective Effects of Fermented Oyster Extract against RANKL-Induced Osteoclastogenesis through Scavenging ROS Generation in RAW 264.7 Cells. International journal of molecular sciences, 20(6), 1439. https://doi.org/10.3390/ijms20061439 Khaliq, H., Juming, Z., & Ke-Mei, P. (2018). The Physiological Role of Boron on Health. Biological trace element research, 186(1), 31–51. https://doi.org/10.1007/s12011-018-1284-3 * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$29.99
GENESIS MALE REVITALIZING FORMULA
Genesis Male Revitalizing Formula contains natural vitamins, minerals and herbs to enhance overall health. These vitamins and herbs also help to support the body’s natural production of testosterone, which can provide multiple benefits as men age. Serving Size: 3 Capsules Servings Per Container: 30 Formula Purposes & Benefits Genesis Blends Male Revitalizing Supplement is formulated to increase natural testosterone levels, sexual function, positive mood, reduced cortisol, increased nitric oxide production, increased muscle mass, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high-quality ingredients. Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Magnesium ● Supports optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91). ● Supports biological reactions such as ATP-fueled reactions and pancreatic insulin secretion (90,91). ● Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91). ● Reduces peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91). Zinc ● Supports immune function, skin health, cognitive function, and vision (172,173). ● Supports stimulation of the innate and adaptive immune system (172,173). ● Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173). ● Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173). Tribulus Terrestris ● Supports sexual function, increased testosterone, cardiovascular health, supports healthy urinary tract function, supports athletic performance, and aids as a neuroprotective agent (137,138). ● Supports sexual health, via activating aphrodisiacs, increased spermatogenesis, sperm motility, increased free testosterone, and increase of androgenic (hormone) action via the activation of endogenous testosterone production (137,138). ● Supports cardiovascular health via decreased arterial inflammation levels of tumor necrosis factor (TNF)-α and interleukin (IL)-6 (137,138). ● Supports neuroprotective properties via protection of neuron injury, and cerebral ischemia–reperfusion by suppressing brain inflammatory markers (NF-κB, TNF-α and IL-1β) (137,138). Chrysin ● Supports immune health, cardiovascular health, and increased testosterone (209). ● Supports immune health via suppression of pro-oxidant enzymes, scavenging free radicals, and reduced inflammatory cytokines (markers of inflammation) (209). ● Supports cardiovascular health via increased bioavailability of endothelial nitric oxide, reduced prevalence of atherosclerosis, reduced thrombogenesis (blood clotting) and reduced vascular (blood vessel) inflammation (209). ● Supports increased testosterone via blocking of androgens into estrogen (210). Horny Goat Weed ● Supports increased sexual drive, increased testosterone, reduced progression of atherosclerosis, increased nitric oxide levels, and reduced arterial (blood vessel) inflammation levels (126,127). ● Reduces arterial inflammation via reduction of free-radical-induced peroxidation in erythrocytes, and increased nitric oxide levels (126,127). ● supports arterial health (health of blood vessels) via attenuating DNA damage, correcting endothelial dysfunction (126,127). ● Represses macrophage-derived foam cell formation, inhibiting platelet activation, and reduces oxLDL-induced monocyte adhesion to endothelial cells (126,127). Longjack (Tongkat Ali) ● Reduces stress hormones (cortisol), increases free testosterone, enhances mood, and supports sexual function (132). Saw Palmetto ● Supports prostate health, cardiovascular health, and increased hair growth (133,134). ● Supports prostate health via anti-androgenic and anti-inflammatory effects resulting in reduced Benign prostatic hyperplasia (134). Hawthorn Berries ● Supports cardiovascular health and combats metabolic syndrome (165). ● Supports cardiovascular health via reduced atherosclerotic lesion areas, reduced cholesterol synthesis (acyl-coA-cholesterol acyltransferase enzyme), reduced very-low-density lipoproteins (VLDL), and inhibited platelet aggregation (165). Cissus Quadrangularis ● Supports joint health, antioxidant function, cardiovascular health, and reduced body fat (211, 212). ● Supports antioxidant function via increased free radical scavenging capacity and reduced inflammatory cytokines (211, 212). ● Supports Cardiovascular health via decreases in the waist and hip circumferences, reduced blood pressure, total cholesterol, triglycerides, fasting blood glucose, and leptin levels (211, 212). ● Reduces body fat via decreased Enzymatic activity of pancreatic lipase and decreased activity of genetic modulators of adipogenesis (fat cell growth) such as C/EBPα, PPARγ, SREBP-1c (genetic regulators of fat cell growth) (211, 212). ● Supports joint health via reduced inflammation in connective tissue (211, 212). Proper Use of This Supplement Suggested Use: Take three (3) capsules before bedtime. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. Uses high-quality nutraceuticals in an effective evidence-based and efficaciously dosed formula. 2. Uses cheap sources of nutraceuticals that contain high amounts of fillers, heavy metals, and in formulated without evidence-based dosages. Sources Boyle, N. B., Lawton, C., & Dye, L. (2017). The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients, 9(5), 429. https://doi.org/10.3390/nu9050429 Verma, H., & Garg, R. (2017). Effect of magnesium supplementation on type 2 diabetes associated cardiovascular risk factors: a systematic review and meta-analysis. Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 30(5), 621–633. https://doi.org/10.1111/jhn.12454 Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.00734 Rehman, S. U., Choe, K., & Yoo, H. H. (2016). Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules (Basel, Switzerland), 21(3), 331. https://doi.org/10.3390/molecules21030331 Dehghani, S., Mehri, S., & Hosseinzadeh, H. (2019). The effects of Crataegus pinnatifida (Chinese hawthorn) on metabolic syndrome: A review. Iranian journal of basic medical sciences, 22(5), 460–468. https://doi.org/10.22038/IJBMS.2019.31964.7678 Maywald, M., Wessels, I., & Rink, L. (2017). Zinc Signals and Immunity. International journal of molecular sciences, 18(10), 2222. https://doi.org/10.3390/ijms18102222 Wessels, I., Rolles, B., & Rink, L. (2020). The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis. Frontiers in immunology, 11, 1712. https://doi.org/10.3389/fimmu.2020.01712 Farkhondeh T, Samarghandian S, Bafandeh F. The Cardiovascular Protective Effects of Chrysin: A Narrative Review on Experimental Researches. Cardiovasc Hematol Agents Med Chem. 2019;17(1):17-27. doi: 10.2174/1871525717666190114145137. PMID: 30648526; PMCID: PMC6865076. Gambelunghe C, Rossi R, Sommavilla M, Ferranti C, Rossi R, Ciculi C, Gizzi S, Micheletti A, Rufini S. Effects of chrysin on urinary testosterone levels in human males. J Med Food. 2003 Winter;6(4):387-90. doi: 10.1089/109662003772519967. PMID: 14977449. Nash R, Azantsa B, Kuate D, Singh H, Oben J. The Use of a Stem and Leaf Aqueous Extract of Cissus quadrangularis (CQR-300) to Reduce Body Fat and Other Components of Metabolic Syndrome in Overweight Participants. J Altern Complement Med. 2019 Jan;25(1):98-106. doi: 10.1089/acm.2018.0016. Epub 2018 Nov 12. PMID: 29912570; PMCID: PMC6352552. Bloomer RJ, Farney TM, McCarthy CG, Lee SR. Cissus quadrangularis reduces joint pain in exercise-trained men: a pilot study. Phys Sportsmed. 2013 Sep;41(3):29-35. doi: 10.3810/psm.2013.09.2021. PMID: 24113700. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$39.99
GENESIS SWEET DREAMS
This blend of natural ingredients include; melatonin, camomile and vitamin B-6. This natural blend has been formulated to aid the body in obtaining more restful sleep. The Genesis Sweet Dreams formula contains relaxing vitamins, minerals and herbs. When taken as directed, Genesis Sweet Dreams can help decrease feelings of worry and stress while falling asleep and sleeping through the night. Serving Size: 2 Capsules Servings Per Container: 30 Formula Purposes & Benefits Genesis Blends Sweet Dreams is formulated to support healthy sleep cycles (circadian rhythm), relaxation, and improved mood. Our product is synthesized utilizing the latest scientific research and formulated with high quality ingredients. Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Formula Ingredient Deck Benefits Of Each Ingredient Calcium Carbonate ● Supports bone health, muscle function, and cardiovascular health (36,37). ● Regulates processes of bone resorption, mineralization, and fracture repair (36,37). ● Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37). ● Prevents the development of preeclampsia (36,37). Vitamin B6 ● Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). ● Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). ● Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). ● May support blood sugar regulation in women with gestational diabetes (40). ● Cofactor for enzymes involved in DNA metabolism (40). Magnesium ● Supports optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91). ● Supports biological reactions such as ATP fueled reactions and pancreatic insulin secretion (90,91). ● Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91). ● Reduces peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91). L-Tryptophan ● Decreases anxiety, supports positive mood, supports gut brain axis, and an improved sleep cycle (259,260). ● Decreases anxiety via increases in 5 HTP (259, 260). ● Improves circadian rhythm via increased natural melatonin production (259,260). ● Supports gut brain axis via natural increased production of serotonin in gut neurons (260). Goji Berry ● Supports immune health, vision health, immune health, and aids as a neuroprotective agent (261,262). ● Supports immune function via carotenoid and polyphenolic free radical scavenging capabilities, reduced DNA damage, and reduced inflammatory cytokines (261). ● Supports vision health via ocular neuroprotective effects zeaxanthin content (found in goji berry) (262). ● Increases neuronal protection with potent ameliorative effects on neuronal oxidative stress, inflammation, apoptosis and neuronal cell death (262). Chamomile ● Supports healthy sleep, relaxation, reduced anxiety, and antioxidant support (251,252,253). ● Supports antioxidant function due to high levels of quercetin (flavonoid antioxidant) (251,252,253). ● Supports sleep via increases in parasympathetic (relaxation mode) activity, increased benzodiazepine-like hypnotic activity (sleep inducer), and attachment to GABA receptors (251,252,253). Lemon Balm ● Supports healthy sleep, relaxation, reduced anxiety, and antioxidant support (254,255). ● Supports antioxidant function via ability to scavenge free radicals, reduce oxidative stress, increased glutathione production (master antioxidant) combat DNA damage (254,225). ● Supports relaxed sleep via enhanced REM cycles reduced stress at bedtime (254,225). Passion Flower ● Reduces stress, enhances sleep, and improved mood (248). ● Enhances positive mood and sleep via regulated gamma‐aminobutyric acid receptor A (GABAA) activity (receptor which controls sleep) (248). L-Taurine ● Supports hydration, increased energy, antioxidant function, and increases fat metabolism during aerobic exercise (242,243). ● Supports antioxidant function via combating reactive oxygen species (243). ● Increases fat metabolism during exercise via enhanced mitochondrial fatty acid oxidation (cells using fat as fuel) (242). Hops ● Combats depression, anxiety, reduces triglycerides and supports a positive mood (246,247). St. John’s Wort ● Combats depression and supports a positive mood (249,250). GABA ● Supports relaxation, positive mood, increased memory, reduced anxiety, blood sugar regulation, and increased growth hormone production (102). Skullcap ● Supports calming mood and relaxation. L-Theanine ● Unique non-protein amino acid found in green tea (Camellia sinensis) (53). ● Supports mood, mental clarity, and cognitive health, memory, and is a natural anti-depressant/neuroprotective agent (53). ● Aids as an antidepressant due to partial antagonism for the N-methyl-D-aspartate receptor manifesting its cognitive optimizing effects (53). ● Reduces the neuropsychiatric side effects of chronic adolescent THC exposure (54). Ashwagandha ● Supports cardiovascular, hormonal, immune, healthy weight loss, mood, and optimized sleep (82,83). ● Reduces stress hormone cortisol resulting in improved body composition, sex hormone profile, and mood (82,83). ● Improves exercise performance via increased V02 max, muscular endurance, muscle hypertrophy (muscle growth), and decreased muscular fatigue (83). ● Improves quality of sleep by enhancing sleep recovery, reducing plasma cortisol concentrations, and enhancing REM sleep cycles (83). ● Supports hormonal and immune health via reduced production of inflammatory molecules (reactive oxygen species) and simultaneous increases in sex hormones (84). Inositol ● Supports liver detoxification, combats metabolic syndrome, and aids as an antioxidant (221). ● Combats metabolic syndrome via reduced levels of triglycerides, total- and LDL-cholesterol (221). ● Supports antioxidant function via reduced levels of reactive oxygen species and inflammatory markers (interleukin 6) (222). 5-HTP ● Supports healthy sleep patterns, mood, reduced anxiety, and supports the gut brain axis (261). ● Supports healthy sleep patterns via enhanced circadian rhythm and increased natural melatonin production (261). ● Supports gut brain axis via natural increased production of serotonin (neurotransmitter) in gut neurons (260, 261). Melatonin ● Supports healthy sleep patterns, immune function, and antioxidant support (256,257, 258). ● Supports healthy circadian rhythms, and improves the onset, duration, and quality of sleep. ● Supports immune function via improved free radical scavenging capacity (258). Valerian Root ● Reduces stress, enhances sleep, and improves mood (244,245). ● Enhances positive mood and sleep via regulated gamma‐aminobutyric acid receptor A (GABAA) activity (receptor which controls sleep) (244, 245). Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules twice a day. For best results, take 20-30 minutes before a meal with an 8 oz glass of water, or as directed by your health care professional. Our Formula Vs Other Formulas on the Market. 1. Uses third party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third party tested have been removed by FDA due to high levels of heavy metals. 2. Uses high quality nutraceuticals in an effective evidence based and efficaciously dosed formula. 2. Uses cheap sources of nutraceuticals that contain high amounts of fillers, heavy metals, and is formulated without evidence based dosages.
$25.99
GENESIS CBD OIL - 2,000 MG FULL SPECTRUM
Serving Size: 1 ml Servings Per Bottle: 30 Bottle Color: Amber Bottle Size: 1 oz (30 ml) Lid Color: Black * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$119.00