Drive & Enhancement
GENESIS ULTRA MEN'S DAILY VITAMIN
Genesis Ultra Men's daily vitamin is focused on the anatomy and nutrient needs of men, geared toward helping them have and maintain proper nutrition. Aiding in mental alertness and increased energy. Contains a complete blend of the essential vitamins and minerals, powerful fruit and berry antioxidants to support detoxing, natural energizers from herbs and berries for a natural energy lift with no caffeine, Serving Size: 2 Capsules Servings Per Container: 30 Formula Purposes & Benefits Genesis Blends Men’s Multivitamin is formulated to support cardiovascular health, hormonal health, metabolic health, immune health, digestive health, sexual function, cognitive function, positive mood, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high-quality ingredients. Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Vitamin A (beta carotene) ● Supports vision health, skin health, immune health, and increases antioxidant support (182, 183). ● Supports antioxidant function via decreased inflammatory cytokines (inflammation), decreased reactive oxygen species, and increased L-glutathione production (master antioxidant) (182, 183). ● Supports visual health via increased amounts of plasma vitamin A in macular (eye) tissues (182,183). Vitamin C ● Supports immune, cardiovascular, skin, cognitive, fat burning, and digestive health (97, 98). ● Supports immune health via increased oxidant, free radical scavenging, and fueling neutrophilic (immune cell) activity in chemotaxis, phagocytosis, and microbial killing (97,98). ● Supports fat burning by increasing carnitine biosynthesis (molecule required for mitochondrial fatty acid oxidation) (97,98). ● Supports accelerate bone healing after a fracture, increase type I collagen synthesis, and reduce oxidative stress (inflammation) (98). Calcium Carbonate ● Supports bone health, muscle function, and cardiovascular health (36,37). ● Regulates processes of bone resorption, mineralization, and fracture repair (36,37). ● Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37). ● Prevents the development of preeclampsia (36,37). Vitamin D ● Supports exercise performance, immune health, muscle growth, optimal bone health, hormonal health, immune function, increased sexual health, cardiovascular health, glucose tolerance, strength, and positive mood (77,78,79). ● Supports hormonal health via high amounts of vitamin D receptor (VDR) activity in hormone based negative feedback loop reactions (77,78). ● Supports cardiovascular health via improved absorption of calcium, reduced atherosclerotic activity, stimulating cardiomyocytes, and improved vascular health (77,78). ● Supports exercise performance via reduced exercise associated inflammation and muscle damage (77,78). ● Supports sexual health via increased activity of Vitamin D receptor activity of testosterone production (79). ● Supports immune function via decreases of inflammatory cytokines and aiding immune cells (77,78). ● Supports joint health via regulating calcium and phosphorus and bone remodeling along with other calcium-regulating actions (77,78). Vitamin E ● Supports immune function, cognitive health, cardiovascular health, and bone health (204,205,206,207,208) ● Supports immune health via neutralizing free radicals and reactive oxygen species, and increased T lymphocyte-mediated immune function (204). ● Supports cardiovascular health via reduced cholesterol (204). ● Supports cognitive function via reduced oxidative stress, inflammation, and DNA damage of neuronal tissues (208). Vitamin B1 (Thiamine) ● Supports aerobic energy metabolism (oxidative phosphorylation), cell growth, optimal neuronal conduction (nerve impulses), and cardiovascular health (94). ● Supports cardiovascular function and aids as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95). Vitamin B2 (Riboflavin) ● Supports conversion and activation of other B vitamins, red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93). Vitamin B3 (Niacin) ● Major B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very-low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9). ● Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9). ● Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9). ● Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9). ● Prevents pathologies(diseases) such as Pellagra and reduces the prevalence of nervous anorexia, cancer, and Crohn’s disease (10, 11). Vitamin B6 ● Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). ● Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). ● Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). ● May support blood sugar regulation in women with gestational diabetes (40). ● Cofactor for enzymes involved in DNA metabolism (40). Vitamin B12 ● Supports proper DNA synthesis, folate cycle function, energy production, cognitive function, and immune health (51,53). ● Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress (51). ● May prevent vitamin b-12 deficiency diseases such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis (53). Zinc ● Supports immune function, skin health, cognitive function, and vision (172,173). ● Supports stimulation of the innate and adaptive immune system (172,173). ● Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173). ● Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173). Biotin ● Supports conversion of food into cellular energy, hair health, skin health, and cognitive function (213,214). ● Enhances glucose breakdown into skeletal muscle tissue (213,214). Vitamin B5 ● Supports energy production, cell growth, cell repair, cognitive function, increased hippocampal volume (memory), and optimized bioenergetics (burning of carbohydrates, fat, and protein) (96). Magnesium ● Supports optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91). ● Supports biological reactions such as ATP-fueled reactions and pancreatic insulin secretion (90,91). ● Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91). ● Reduces peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91). Copper ● Supports healthy blood sugar levels, energy metabolism and cholesterol management (143,144). Selenium ● Supports antioxidant function, cardiovascular health, cognitive function, thyroid health, and immune health (145, 146). ● Combats atherosclerosis, high cholesterol (hypercholesterolemia), and type 1 diabetes (147). ● Supports thyroid health via decreased circulating thyroid autoantibodies in patients with chronic autoimmune thyroiditis (AIT) (146). ● Increases the activity of selenoproteins that decrease reactive oxygen species (inflammation), increases natural killer activity, and increases glutathione (master antioxidant) levels (145,147). Manganese ● Supports enzymatic antioxidant reactions, increased bone mineral density, and blood sugar regulation (148,149). Molybdenum ● Increases enzymatic reactions involved in sulfite metabolism and detoxification (150). Chromium ● Supports insulin function, reduced cholesterol, improved blood sugar regulation, and may lower cholesterol (218,219). Lutein ● A carotenoid that supports vision health, immune health, cardiovascular health, and combats diabetic retinopathy (155,156). ● Supports increased lutein concentration in the macula and exhibits various features such as anti-inflammatory, anti-oxidative, and blue light-filtering effects (155,156). ● Supports visual health via increased lutein concentration in the macular layer of the retina, reduced susceptibility to age-related macular disease, reduced prevalence of cataracts, and improved plasma level of lutein and retinal macular pigment level (155,156). Lycopene ● Supports prostate health, cardiovascular support, antioxidant, anti-inflammatory, and chemoprotective properties against cancer (191,192, 193). ● Combats inflammation via scavenging of free radicals and reduces oxidative damage of DNA. (191,192,193). ● Combats carcinogenesis via carcinogen-metabolizing enzymes, apoptosis (cancer cell death), anti-proliferation, pro-differentiation, and anti-lipid peroxidation activities. (193). ● Inhibits phosphorylation of anti-oncogenes such as p53 and Rb. It also inhibits G0/G1 and S-phase of the cell cycle (193). Spirulina ● Supports reduced cholesterol, blood pressure, blood sugar regulation, reduces inflammation, reduced body fat, and supports antioxidant function (301, 302). Goldenseal Root ● Supports digestive health, antibacterial activity, and antioxidant support (201, 202). ● Supports antioxidant function via levels of berberine (alkaloid) (201,202). Echinacea ● Increases antiviral, anti-microbial, antioxidant capacity, and supports a strong immune system (159,160). ● Supports immune health via decreased impro-inflammatory markers (cytokines IL-6, IL-8, and TNF) (159,160). ● Supports adaptive and innate immunity via increased monocytes, neutrophils, natural killer cells, and CD8 T cells (159,160). Garlic ● Supports cardiovascular health, immune health, joint health, reduced inflammation, gut health, and enhanced antibacterial activity (161). ● Supports cardiovascular health via reduced hypertension, reduced total cholesterol, reduced arterial stiffness (hardening of arteries), and markers of atherosclerosis (161). ● Supports joint health via reduced NF-κB activation (inflammation) in human fibroblasts cells and reduced prevalence of pain in individuals with rheumatoid arthritis (162). ● Supports gut health via increased prebiotic properties, increased microbiome population, and increased Lactobacillus and Clostridia species (163). ● Supports immune health via a reduction in inflammatory markers (CRP, TNF, IL-6) (164). Green Tea Extract ● A potent polyphenolic antioxidant that supports blood pressure, insulin sensitivity, and metabolic health (25). ● High in ECGC (epigallocatechin gallate) (25). ● ECGC is shown to reduce body fat mass, increase fat oxidation(burning) and increase caloric expenditure during exercise. (25). ● Potent anti-inflammatory compound supporting glutathione production and inhibition of pro-inflammatory markers (cytokines). (26). ● Reduces oxidative stress (chronic inflammation in the body) (26). Hawthorn Berries ● Supports cardiovascular health and combats metabolic syndrome (165). ● Supports cardiovascular health via reduced atherosclerotic lesion areas, reduced cholesterol synthesis (acyl-coA-cholesterol acyltransferase enzyme), reduced very-low-density lipoproteins (VLDL), and inhibited platelet aggregation (165). Cinnamon Bark Extract ● Supports blood sugar regulation and cardiovascular health (166). ● Decreases levels of fasting plasma glucose, total cholesterol, LDL-C, triglyceride levels, and an increase in HDL-C levels (166). ● Supports blood sugar regulation by improving insulin sensitivity and enhanced glucose uptake (166). Bilberry Fruit Extract ● Supports vision health, cardiovascular function, increased nitric oxide production, blood sugar regulation, and antioxidant support (167,168). Grape Seed Extract ● Supports increased nitric oxide production, reduces blood pressure, reduces DNA damage, increases collagen production, increases bone strength, and aids as a neuroprotective agent (31). ● Supports antioxidant function via modulation of antioxidant enzyme expression, protection against oxidative damage, and reduced reactive oxygen species (31). ● Supports cardiovascular health via reduced atherosclerosis, inhibiting lipid peroxidation, and improved endothelial vascular function (31). Black Currant ● Supports immune function via high levels of polyphenols and reduction of inflammation (169). ● Supports cardiovascular health via reductions in LDL Cholesterol (169). Pomegranate Extract ● Supports reduced blood pressure, increased nitric oxide production, immune health, blood sugar regulation, prostate health, gut health and aids as an antimicrobial compound (170). ● Supports prostate health via high polyphenolic antioxidant levels (three times the antioxidant activity of green tea) that protect the prostate gland from inflammation (170). ● Supports reduced blood pressure via increased nitric oxide production, increased cardiac output (blood flow), and reduced cholesterol levels (170. ● Supports digestive health via combating inflammatory bowel disease (171). ● Supports immune health via reduced inflammatory cytokines (markers of inflammation) throughout the body (171). Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules once a day. For best results, light exercise and a sensible diet are recommended. Use this product for no less than 8 weeks for maximum results. Do not exceed 4 capsules a day. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. High-quality vitamins, minerals, herbs and nootropics in an effective and efficaciously dosed formula. 2. Uses cheap sources of vitamins, minerals, herbs, and nootropics that contain high amounts of fillers and heavy metals.
$19.99
GENESIS ULTRA WOMEN'S DAILY MULTIVITAMIN
Genesis Ultra multivitamin for Women is A balanced blend of antioxidants, herbs, vitamins and minerals that have been especially formulated to support A woman’s lifestyle and well-being. Serving Size: 2 Capsules Servings Per Container: 30 Formula Purposes & Benefits Genesis Blends Ultra for Women is formulated to support cardiovascular health, hormonal health, metabolic health, immune health, digestive health, sexual function, cognitive function, positive mood, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high-quality ingredients. Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Vitamin A (beta carotene) ● Supports vision health, skin health, immune health, and increases antioxidant support (182, 183). ● Supports antioxidant function via decreased inflammatory cytokines (inflammation), decreased reactive oxygen species, and increased L-glutathione production (master antioxidant) (182,183). ● Supports visual health via increased amounts of plasma vitamin A in macular (eye) tissues (182,183). Vitamin C ● Supports immune, cardiovascular, skin, cognitive, fat burning, and digestive health (97, 98). ● Supports immune health via increased oxidant, free radical scavenging, and fueling neutrophilic (immune cell) activity in chemotaxis, phagocytosis, and microbial killing (97,98). ● Supports fat burning by increasing carnitine biosynthesis (molecule required for mitochondrial fatty acid oxidation) (97,98). ● Supports accelerate bone healing after a fracture, increase type I collagen synthesis, and reduce oxidative stress (inflammation) (98). Calcium Carbonate ● Supports bone health, muscle function, and cardiovascular health (36,37). ● Regulates processes of bone resorption, mineralization, and fracture repair (36,37). ● Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37). ● Prevents the development of preeclampsia (36,37). Vitamin D ● Supports exercise performance, immune health, muscle growth, optimal bone health, hormonal health, immune function, increased sexual health, cardiovascular health, glucose tolerance, strength, and positive mood (77,78,79). ● Supports hormonal health via high amounts of vitamin D receptor (VDR) activity in hormone-based negative feedback loop reactions (77,78). ● Supports cardiovascular health via improved absorption of calcium, reduced atherosclerotic activity, stimulating cardiomyocytes, and improved vascular health (77,78). ● Supports exercise performance via reduced exercise-associated inflammation and muscle damage (77,78). ● Supports sexual health via increased activity of Vitamin D receptor activity of testosterone production (79). ● Supports immune function via decreases of inflammatory cytokines and aiding immune cells (77,78). ● Supports joint health via regulating calcium and phosphorus and bone remodeling along with other calcium-regulating actions (77,78). Vitamin E ● Supports immune function, cognitive health, cardiovascular health, and bone health (204,205,206,207,208) ● Supports immune health via neutralizing free radicals and reactive oxygen species, and increased T lymphocyte-mediated immune function (204). ● Supports cardiovascular health via reduced cholesterol (204). ● Supports cognitive function via reduced oxidative stress, inflammation, and DNA damage of neuronal tissues (208). Vitamin B1 (Thiamine) ● Supports aerobic energy metabolism (oxidative phosphorylation), cell growth, optimal neuronal conduction (nerve impulses), and cardiovascular health (94). ● Supports cardiovascular function and aids as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95). Vitamin B2 (Riboflavin) ● Supports conversion and activation of other B vitamins, red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93). Vitamin B3 (Niacin) ● Major B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very-low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9). ● Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9). ● Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9). ● Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9). ● Prevents pathologies(diseases) such as Pellagra and reduces the prevalence of nervous anorexia, cancer, and Crohn’s disease (10, 11). Vitamin B6 ● Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). ● Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). ● Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). ● May support blood sugar regulation in women with gestational diabetes (40). ● Cofactor for enzymes involved in DNA metabolism (40). Vitamin B12 ● Supports proper DNA synthesis, folate cycle function, energy production, cognitive function, and immune health (51,53). ● Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress (51). ● May prevent vitamin b-12 deficiency diseases such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis (53). Zinc ● Supports immune function, skin health, cognitive function, and vision (172,173). ● Supports stimulation of the innate and adaptive immune system (172,173). ● Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173). ● Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173). Biotin ● Supports conversion of food into cellular energy, hair health, skin health, and cognitive function (213,214). ● Enhances glucose breakdown into skeletal muscle tissue (213,214). Vitamin B5 ● Supports energy production, cell growth, cell repair, cognitive function, increased hippocampal volume (memory), and optimized bioenergetics (burning of carbohydrates, fat, and protein) (96). Magnesium ● Supports optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91). ● Supports biological reactions such as ATP-fueled reactions and pancreatic insulin secretion (90,91). ● Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91). ● Reduces peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91). Copper ● Supports healthy blood sugar levels, energy metabolism and cholesterol management (143,144). Selenium ● Supports antioxidant function, cardiovascular health, cognitive function, thyroid health, and immune health (145, 146). ● Combats atherosclerosis, high cholesterol (hypercholesterolemia), and type 1 diabetes (147). ● Supports thyroid health via decreased circulating thyroid autoantibodies in patients with chronic autoimmune thyroiditis (AIT) (146). ● Increases the activity of selenoproteins that decrease reactive oxygen species (inflammation), increases natural killer activity, and increases glutathione (master antioxidant) levels (145,147). Manganese ● Supports enzymatic antioxidant reactions, increased bone mineral density, and blood sugar regulation (148,149). Molybdenum ● Increases enzymatic reactions involved in sulfite metabolism and detoxification (150). Chromium ● Supports insulin function, reduced cholesterol, improved blood sugar regulation and may lower cholesterol (218,219). Wild Yam Extract ● May support hormonal balance in women via increased progesterone production (151). ● Supports the reduction of atherosclerosis and improved vascular flow (151). Red Clover Extract ● Supports menopausal health via reductions in hot flashes, increased estrogen production, antioxidant support, improved lipid panels, increased bone mineral density, and improved mood (152,153,154). ● High in phytoestrogens (isoflavone) that bind to estrogen receptors which increase estradiol (154). ● Reduces total cholesterol, LDL, triglycerides, and improves HDL (152,153,154). ● Supports bone health via increased osteoblasts (cells that build bone) activity, reduced bone turnover by inhibiting bone reabsorption, and increased bone mineral density (152,153,154). Lutein ● A carotenoid that supports vision health, immune health, cardiovascular health, and combats diabetic retinopathy (155,156). ● Supports increased lutein concentration in the macula and exhibits various features such as anti-inflammatory, anti-oxidative, and blue light-filtering effects (155,156). ● Supports visual health via increased lutein concentration in the macular layer of the retina, reduced susceptibility to age-related macular disease, reduced prevalence of cataracts, and improved plasma level of lutein and retinal macular pigment level (155,156). Cranberry Extract ● Supports cardiovascular health, immune health, and may combat against urinary tract infections (156, 157). Alpha Lipoic Acid ● Supports immune health, cardiovascular health, blood sugar regulation, reduced body fat, and improved cognitive function (158). ● Supports blood sugar regulation via increased glucose uptake in insulin-sensitive and insulin-resistant muscle (158). ● Supports cardiovascular health via increased nitric oxide production and decreased glycation of red blood cells (decreased HA1C) (158). ● Supports cognitive function via enhanced memory, focus, and reduction of neurodegenerative disease (158). ● Supports immune health via increased free radical scavenging capabilities and increased glutathione (master antioxidant) levels (158). ● Reduces body weight via decreased appetite in individuals with metabolic syndrome (158). Goldenseal Root ● Supports digestive health, antibacterial activity, and antioxidant support (201, 202). ● Supports antioxidant function via levels of berberine (alkaloid) (201,202). Echinacea ● Increases antiviral, anti-microbial, antioxidant capacity, and supports a strong immune system (159,160). ● Supports immune health via decreased impro-inflammatory markers (cytokines IL-6, IL-8, and TNF) (159,160). ● Supports adaptive and innate immunity via increased monocytes, neutrophils, natural killer cells, and CD8 T cells (159,160). Spirulina ● Supports reduced cholesterol, blood pressure, blood sugar regulation, reduces inflammation, reduced body fat, and supports antioxidant function (301, 302). Garlic ● Supports cardiovascular health, immune health, joint health, reduced inflammation, gut health, and enhanced antibacterial activity (161). ● Supports cardiovascular health via reduced hypertension, reduced total cholesterol, reduced arterial stiffness (hardening of arteries), and markers of atherosclerosis (161). ● Supports joint health via reduced NF-κB activation (inflammation) in human fibroblasts cells and reduced prevalence of pain in individuals with rheumatoid arthritis (162). ● Supports gut health via increased prebiotic properties, increased microbiome population, and increased Lactobacillus and Clostridia species (163). ● Supports immune health via a reduction in inflammatory markers (CRP, TNF, IL-6) (164). Green Tea Extract ● A potent polyphenolic antioxidant that supports blood pressure, insulin sensitivity, and metabolic health (26). ● High in ECGC (epigallocatechin gallate) (26). ● ECGC is shown to reduce body fat mass, increase fat oxidation(burning) and increase caloric expenditure during exercise (25). ● Potent anti-inflammatory compound supporting glutathione production and inhibition of pro-inflammatory markers (cytokines) (26). ● Reduces oxidative stress (chronic inflammation in the body) (26). Hawthorn Berries ● Supports cardiovascular health and combats metabolic syndrome (165). ● Supports cardiovascular health via reduced atherosclerotic lesion areas, reduced cholesterol synthesis (acyl-coA-cholesterol acyltransferase enzyme), reduced very-low-density lipoproteins (VLDL), and inhibited platelet aggregation (165). Cinnamon Bark Extract ● Supports blood sugar regulation and cardiovascular health (166). ● Decreases levels of fasting plasma glucose, total cholesterol, LDL-C, triglyceride levels, and an increase in HDL-C levels (166). ● Supports blood sugar regulation by improving insulin sensitivity and enhanced glucose uptake (166). Bilberry Fruit Extract ● Supports vision health, cardiovascular function, increased nitric oxide production, blood sugar regulation, and antioxidant support (167,168). Grape Seed Extract ● Supports increased nitric oxide production, reduces blood pressure, reduces DNA damage, increases collagen production, increases bone strength, and aids as a neuroprotective agent (31). ● Supports antioxidant function via modulation of antioxidant enzyme expression, protection against oxidative damage, and reduced reactive oxygen species (31). ● Supports cardiovascular health via reduced atherosclerosis, inhibiting lipid peroxidation, and improved endothelial vascular function (31). Black Currant ● Supports immune function via high levels of polyphenols and reduction of inflammation (169). ● Supports cardiovascular health via reductions in LDL Cholesterol (169). Pomegranate Extract ● Supports reduced blood pressure, increased nitric oxide production, immune health, blood sugar regulation, prostate health, gut health and aids as an antimicrobial compound (170). ● Supports prostate health via high polyphenolic antioxidant levels (three times the antioxidant activity of green tea) that protect the prostate gland from inflammation (170). ● Supports reduced blood pressure via increased nitric oxide production, increased cardiac output (blood flow), and reduced cholesterol levels (170. ● Supports digestive health via combating inflammatory bowel disease (171). ● Supports immune health via reduced inflammatory cytokines (markers of inflammation) throughout the body (171). Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules once a day. For best results, light exercise and a sensible diet are recommended. Use this product for no less than 8 weeks for maximum results. Do not exceed 4 capsules a day. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. High-quality vitamins, minerals, herbs and nootropics in an effective and efficaciously dosed formula. 2. Uses cheap sources of vitamins, minerals, herbs, and nootropics that contain high amounts of fillers and heavy metals. Sources 1.Sureda, A., & Pons, A. (2012). Arginine and citrulline supplementation in sports and exercise: ergogenic nutrients?. Medicine and sport science, 59, 18–28. https://doi.org/10.1159/000341937 2.Szefel, J., Danielak, A., & Kruszewski, W. J. (2019). Metabolic pathways of L-arginine and therapeutic consequences in tumors. Advances in medical sciences, 64(1), 104–110. https://doi.org/10.1016/j.advms.2018.08.018 3.Rodrigues-Krause, J., Krause, M., Rocha, I., Umpierre, D., & Fayh, A. (2018). Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis. Nutrients, 11(1), 15. https://doi.org/10.3390/nu11010015 4.Hu, S., Han, M., Rezaei, A., Li, D., Wu, G., & Ma, X. (2017). L-Arginine Modulates Glucose and Lipid Metabolism in Obesity and Diabetes. Current protein & peptide science, 18(6), 599–608. https://doi.org/10.2174/1389203717666160627074017 9.Gasperi, V., Sibilano, M., Savini, I., & Catani, M. V. (2019). Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications. International journal of molecular sciences, 20(4), 974. https://doi.org/10.3390/ijms20040974 10.Gentilcore D. (2016). Louis Sambon and the Clash of Pellagra Etiologies in Italy and the United States, 1905-14. Journal of the history of medicine and allied sciences, 71(1), 19–42. https://doi.org/10.1093/jhmas/jrv002 11.Kirkland J. B. (2009). Niacin status and treatment-related leukemogenesis. Molecular cancer therapeutics, 8(4), 725–732. https://doi.org/10.1158/1535-7163.MCT-09-0042 12.Hoskin, P., Rojas, A., & Saunders, M. (2009). Accelerated radiotherapy, carbogen, and nicotinamide (ARCON) in the treatment of advanced bladder cancer: mature results of a Phase II nonrandomized study. International journal of radiation oncology, biology, physics, 73(5), 1425–1431. https://doi.org/10.1016/j.ijrobp.2008.06.1950 Khaing, W., Vallibhakara, S. A., Tantrakul, V., Vallibhakara, O., Rattanasiri, S., McEvoy, M., Attia, J., & Thakkinstian, A. (2017). Calcium and Vitamin D Supplementation for Prevention of Preeclampsia: A Systematic Review and Network Meta-Analysis. Nutrients, 9(10), 1141. https://doi.org/10.3390/nu9101141 Courteix, D., Jaffré, C., Lespessailles, E., & Benhamou, L. (2005). Cumulative effects of calcium supplementation and physical activity on bone accretion in premenarchal children: a double-blind randomised placebo-controlled trial. International journal of sports medicine, 26(5), 332–338. https://doi.org/10.1055/s-2004-821040 Ueland, P. M., McCann, A., Midttun, Ø., & Ulvik, A. (2017). Inflammation, vitamin B6 and related pathways. Molecular aspects of medicine, 53, 10–27. https://doi.org/10.1016/j.mam.2016.08.001 Bird R. P. (2018). The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis. Advances in food and nutrition research, 83, 151–194. https://doi.org/10.1016/bs.afnr.2017.11.004 Mascolo, E., & Vernì, F. (2020). Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms. International journal of molecular sciences, 21(10), 3669. https://doi.org/10.3390/ijms21103669 van de Lagemaat, E. E., de Groot, L., & van den Heuvel, E. (2019). Vitamin B12in Relation to Oxidative Stress: A Systematic Review. Nutrients, 11(2), 482. https://doi.org/10.3390/nu11020482 Romain, M., Sviri, S., Linton, D. M., Stav, I., & van Heerden, P. V. (2016). The role of Vitamin B12 in the critically ill--a review. Anaesthesia and intensive care, 44(4), 447–452. https://doi.org/10.1177/0310057X1604400410 Shipton, M. J., & Thachil, J. (2015). Vitamin B12 deficiency - A 21st century perspective . Clinical medicine (London, England), 15(2), 145–150. https://doi.org/10.7861/clinmedicine.15-2-145 Hoffer, L. J., Sher, K., Saboohi, F., Bernier, P., MacNamara, E. M., & Rinzler, D. (2003). N-acetyl-L-tyrosine as a tyrosine source in adult parenteral nutrition. JPEN. Journal of parenteral and enteral nutrition, 27(6), 419–422. https://doi.org/10.1177/0148607103027006419 Ipson, B. R., & Fisher, A. L. (2016). Roles of the tyrosine isomers meta-tyrosine and ortho-tyrosine in oxidative stress. Ageing research reviews, 27, 93–107. https://doi.org/10.1016/j.arr.2016.03.005 Langade, D., Kanchi, S., Salve, J., Debnath, K., & Ambegaokar, D. (2019). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus, 11(9), e5797. https://doi.org/10.7759/cureus.5797 Bonilla, D. A., Moreno, Y., Gho, C., Petro, J. L., Odriozola-Martínez, A., & Kreider, R. B. (2021). Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis. Journal of functional morphology and kinesiology, 6(1), 20. https://doi.org/10.3390/jfmk6010020 Boyle, N. B., Lawton, C., & Dye, L. (2017). The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients, 9(5), 429. https://doi.org/10.3390/nu9050429 Verma, H., & Garg, R. (2017). Effect of magnesium supplementation on type 2 diabetes associated cardiovascular risk factors: a systematic review and meta-analysis. Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 30(5), 621–633. https://doi.org/10.1111/jhn.12454 Thakur, K., Tomar, S. K., Singh, A. K., Mandal, S., & Arora, S. (2017). Riboflavin and health: A review of recent human research. Critical reviews in food science and nutrition, 57(17), 3650–3660. https://doi.org/10.1080/10408398.2016.1145104 Suwannasom, N., Kao, I., Pruß, A., Georgieva, R., & Bäumler, H. (2020). Riboflavin: The Health Benefits of a Forgotten Natural Vitamin. International journal of molecular sciences, 21(3), 950. https://doi.org/10.3390/ijms21030950 DiNicolantonio, J. J., Niazi, A. K., Lavie, C. J., O'Keefe, J. H., & Ventura, H. O. (2013). Thiamine supplementation for the treatment of heart failure: a review of the literature. Congestive heart failure (Greenwich, Conn.), 19(4), 214–222. https://doi.org/10.1111/chf.12037 Saedisomeolia, A., & Ashoori, M. (2018).Thiamine in Human Health: A Review of Current Evidences. Advances in food and nutrition research, 83, 57–81. https://doi.org/10.1016/bs.afnr.2017.11.002 Ragaller, V., Lebzien, P., Südekum, K. H., Hüther, L., & Flachowsky, G. (2011). Pantothenic acid in ruminant nutrition: a review. Journal of animal physiology and animal nutrition, 95(1), 6–16. https://doi.org/10.1111/j.1439-0396.2010.01004.x Carr, A. C., & Maggini, S. (2017). Vitamin C and Immune Function. Nutrients, 9(11), 1211. https://doi.org/10.3390/nu9111211 DePhillipo, N. N., Aman, Z. S., Kennedy, M. I., Begley, J. P., Moatshe, G., & LaPrade, R. F. (2018). Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review. Orthopaedic journal of sports medicine, 6(10), 2325967118804544. https://doi.org/10.1177/2325967118804544 Hasani, H., Arab, A., Hadi, A., Pourmasoumi, M., Ghavami, A., & Miraghajani, M. (2019). Does ginger supplementation lower blood pressure? A systematic review and meta-analysis of clinical trials. Phytotherapy research : PTR, 33(6), 1639–1647. https://doi.org/10.1002/ptr.6362 Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.00734 13.Dording, C. M., Schettler, P. J., Dalton, E. D., Parkin, S. R., Walker, R. S., Fehling, K. B., Fava, M., & Mischoulon, D. (2015). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evidence-based complementary and alternative medicine : eCAM, 2015, 949036. https://doi.org/10.1155/2015/949036 Pathania, R., Chawla, P., Khan, H., Kaushik, R., & Khan, M. A. (2020). An assessment of potential nutritive and medicinal properties of Mucuna pruriens: a natural food legume. 3 Biotech, 10(6), 261. https://doi.org/10.1007/s13205-020-02253-x Rakesh B, Praveen N (2020) Chapter-10 biotechnological approaches for the production of l-DOPA: a novel and potent anti-Parkinson’s Drug from Mucuna pruriens (L.) DC. Chief Editor: 179 Majekodunmi, S. O., Oyagbemi, A. A., Umukoro, S., & Odeku, O. A. (2011). Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract. Asian Pacific journal of tropical medicine, 4(8), 632–636. https://doi.org/10.1016/S1995-7645(11)60161-2 Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells. Nitric oxide : biology and chemistry, 76, 81–86. https://doi.org/10.1016/j.niox.2018.03.010 Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Saudan, C., Baume, N., Emery, C., Strahm, E., & Saugy, M. (2008). Short term impact of Tribulus terrestris intake on doping control analysis of endogenous steroids. Forensic science international, 178(1), e7–e10. https://doi.org/10.1016/j.forsciint.2008.01.003 Palacios, S., Soler, E., Ramírez, M., Lilue, M., Khorsandi, D., & Losa, F. (2019). Effect of a multi-ingredient based food supplement on sexual function in women with low sexual desire. BMC women's health, 19(1), 58. https://doi.org/10.1186/s12905-019-0755-9 Das, S., & Bisht, S. S. (2013). The bioactive and therapeutic potential of Hemidesmus indicus R. Br. (Indian Sarsaparilla) root. Phytotherapy research : PTR, 27(6), 791–801. https://doi.org/10.1002/ptr.4788 She, T., Qu, L., Wang, L., Yang, X., Xu, S., Feng, J., Gao, Y., Zhao, C., Han, Y., Cai, S., & Shou, C. (2015). Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy via Redox-Dependent ERK1/2 Pathway. Cancer prevention research (Philadelphia, Pa.), 8(5), 464–474. https://doi.org/10.1158/1940-6207.CAPR-14-0372 Majumdar, S., Gupta, S., Prajapati, S. K., & Krishnamurthy, S. (2021). Neuro-nutraceutical potential of Asparagus racemosus: A review. Neurochemistry international, 145, 105013. https://doi.org/10.1016/j.neuint.2021.105013 Gombart, A. F., Pierre, A., & Maggini, S. (2020). A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients, 12(1), 236. https://doi.org/10.3390/nu12010236 Heffernan, S. M., Horner, K., De Vito, G., & Conway, G. E. (2019). The Role of Mineral and Trace Element Supplementation in Exercise and Athletic Performance: A Systematic Review. Nutrients, 11(3), 696. https://doi.org/10.3390/nu11030696 Mock DM. Biotin: From Nutrition to Therapeutics. J Nutr. 2017 Aug;147(8):1487-1492. doi: 10.3945/jn.116.238956. Epub 2017 Jul 12. PMID: 28701385; PMCID: PMC5525106. Patel DP, Swink SM, Castelo-Soccio L. A Review of the Use of Biotin for Hair Loss. Skin Appendage Disord. 2017 Aug;3(3):166-169. doi: 10.1159/000462981. Epub 2017 Apr 27. PMID: 28879195; PMCID: PMC5582478. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$19.99
GENESIS MALE REVITALIZING FORMULA
Genesis Male Revitalizing Formula contains natural vitamins, minerals and herbs to enhance overall health. These vitamins and herbs also help to support the body’s natural production of testosterone, which can provide multiple benefits as men age. Serving Size: 3 Capsules Servings Per Container: 30 Formula Purposes & Benefits Genesis Blends Male Revitalizing Supplement is formulated to increase natural testosterone levels, sexual function, positive mood, reduced cortisol, increased nitric oxide production, increased muscle mass, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high-quality ingredients. Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Magnesium ● Supports optimal nerve function, muscle contractions, cardiovascular, bone health, and decreased anxiety (90,91). ● Supports biological reactions such as ATP-fueled reactions and pancreatic insulin secretion (90,91). ● Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91). ● Reduces peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91). Zinc ● Supports immune function, skin health, cognitive function, and vision (172,173). ● Supports stimulation of the innate and adaptive immune system (172,173). ● Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173). ● Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173). Tribulus Terrestris ● Supports sexual function, increased testosterone, cardiovascular health, supports healthy urinary tract function, supports athletic performance, and aids as a neuroprotective agent (137,138). ● Supports sexual health, via activating aphrodisiacs, increased spermatogenesis, sperm motility, increased free testosterone, and increase of androgenic (hormone) action via the activation of endogenous testosterone production (137,138). ● Supports cardiovascular health via decreased arterial inflammation levels of tumor necrosis factor (TNF)-α and interleukin (IL)-6 (137,138). ● Supports neuroprotective properties via protection of neuron injury, and cerebral ischemia–reperfusion by suppressing brain inflammatory markers (NF-κB, TNF-α and IL-1β) (137,138). Chrysin ● Supports immune health, cardiovascular health, and increased testosterone (209). ● Supports immune health via suppression of pro-oxidant enzymes, scavenging free radicals, and reduced inflammatory cytokines (markers of inflammation) (209). ● Supports cardiovascular health via increased bioavailability of endothelial nitric oxide, reduced prevalence of atherosclerosis, reduced thrombogenesis (blood clotting) and reduced vascular (blood vessel) inflammation (209). ● Supports increased testosterone via blocking of androgens into estrogen (210). Horny Goat Weed ● Supports increased sexual drive, increased testosterone, reduced progression of atherosclerosis, increased nitric oxide levels, and reduced arterial (blood vessel) inflammation levels (126,127). ● Reduces arterial inflammation via reduction of free-radical-induced peroxidation in erythrocytes, and increased nitric oxide levels (126,127). ● supports arterial health (health of blood vessels) via attenuating DNA damage, correcting endothelial dysfunction (126,127). ● Represses macrophage-derived foam cell formation, inhibiting platelet activation, and reduces oxLDL-induced monocyte adhesion to endothelial cells (126,127). Longjack (Tongkat Ali) ● Reduces stress hormones (cortisol), increases free testosterone, enhances mood, and supports sexual function (132). Saw Palmetto ● Supports prostate health, cardiovascular health, and increased hair growth (133,134). ● Supports prostate health via anti-androgenic and anti-inflammatory effects resulting in reduced Benign prostatic hyperplasia (134). Hawthorn Berries ● Supports cardiovascular health and combats metabolic syndrome (165). ● Supports cardiovascular health via reduced atherosclerotic lesion areas, reduced cholesterol synthesis (acyl-coA-cholesterol acyltransferase enzyme), reduced very-low-density lipoproteins (VLDL), and inhibited platelet aggregation (165). Cissus Quadrangularis ● Supports joint health, antioxidant function, cardiovascular health, and reduced body fat (211, 212). ● Supports antioxidant function via increased free radical scavenging capacity and reduced inflammatory cytokines (211, 212). ● Supports Cardiovascular health via decreases in the waist and hip circumferences, reduced blood pressure, total cholesterol, triglycerides, fasting blood glucose, and leptin levels (211, 212). ● Reduces body fat via decreased Enzymatic activity of pancreatic lipase and decreased activity of genetic modulators of adipogenesis (fat cell growth) such as C/EBPα, PPARγ, SREBP-1c (genetic regulators of fat cell growth) (211, 212). ● Supports joint health via reduced inflammation in connective tissue (211, 212). Proper Use of This Supplement Suggested Use: Take three (3) capsules before bedtime. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. Uses high-quality nutraceuticals in an effective evidence-based and efficaciously dosed formula. 2. Uses cheap sources of nutraceuticals that contain high amounts of fillers, heavy metals, and in formulated without evidence-based dosages. Sources Boyle, N. B., Lawton, C., & Dye, L. (2017). The Effects of Magnesium Supplementation on Subjective Anxiety and Stress-A Systematic Review. Nutrients, 9(5), 429. https://doi.org/10.3390/nu9050429 Verma, H., & Garg, R. (2017). Effect of magnesium supplementation on type 2 diabetes associated cardiovascular risk factors: a systematic review and meta-analysis. Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 30(5), 621–633. https://doi.org/10.1111/jhn.12454 Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.00734 Rehman, S. U., Choe, K., & Yoo, H. H. (2016). Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules (Basel, Switzerland), 21(3), 331. https://doi.org/10.3390/molecules21030331 Dehghani, S., Mehri, S., & Hosseinzadeh, H. (2019). The effects of Crataegus pinnatifida (Chinese hawthorn) on metabolic syndrome: A review. Iranian journal of basic medical sciences, 22(5), 460–468. https://doi.org/10.22038/IJBMS.2019.31964.7678 Maywald, M., Wessels, I., & Rink, L. (2017). Zinc Signals and Immunity. International journal of molecular sciences, 18(10), 2222. https://doi.org/10.3390/ijms18102222 Wessels, I., Rolles, B., & Rink, L. (2020). The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis. Frontiers in immunology, 11, 1712. https://doi.org/10.3389/fimmu.2020.01712 Farkhondeh T, Samarghandian S, Bafandeh F. The Cardiovascular Protective Effects of Chrysin: A Narrative Review on Experimental Researches. Cardiovasc Hematol Agents Med Chem. 2019;17(1):17-27. doi: 10.2174/1871525717666190114145137. PMID: 30648526; PMCID: PMC6865076. Gambelunghe C, Rossi R, Sommavilla M, Ferranti C, Rossi R, Ciculi C, Gizzi S, Micheletti A, Rufini S. Effects of chrysin on urinary testosterone levels in human males. J Med Food. 2003 Winter;6(4):387-90. doi: 10.1089/109662003772519967. PMID: 14977449. Nash R, Azantsa B, Kuate D, Singh H, Oben J. The Use of a Stem and Leaf Aqueous Extract of Cissus quadrangularis (CQR-300) to Reduce Body Fat and Other Components of Metabolic Syndrome in Overweight Participants. J Altern Complement Med. 2019 Jan;25(1):98-106. doi: 10.1089/acm.2018.0016. Epub 2018 Nov 12. PMID: 29912570; PMCID: PMC6352552. Bloomer RJ, Farney TM, McCarthy CG, Lee SR. Cissus quadrangularis reduces joint pain in exercise-trained men: a pilot study. Phys Sportsmed. 2013 Sep;41(3):29-35. doi: 10.3810/psm.2013.09.2021. PMID: 24113700. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$39.99
GENESIS MALE ENHANCEMENT FORMULA
Genesis Male Enhancement Formula provides a blend of ingredients that may help to support stamina and sexual libido. Some of the main ingredients in this supplement are: Tongkat Ali, L-Arginine, vitamin b12, and bioperine. Serving Size: 2 Capsules Capsules Per Container: 60 Formula Purposes & Benefits Genesis Blends Male Enhancement Supplement is formulated to increase natural testosterone levels, positive mood, reduced cortisol, increased nitric oxide production, increased muscle mass, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high quality Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards. Formula Ingredient Deck Benefits Of Each Ingredient Horny Goat Weed ● Supports increased sexual drive, increased testosterone, reduced progression of atherosclerosis, increased nitric oxide levels, and reduced arterial (blood vessel) inflammation levels (126,127). ● Reduces arterial inflammation via reduction of free-radical-induced peroxidation in erythrocytes, and increased nitric oxide levels (126,127). ● Supports arterial health (health of blood vessels) via attenuating DNA damage, correcting endothelial dysfunction (126,127). ● represses macrophage-derived foam cell formation, inhibiting platelet activation, and reduces oxLDL-induced monocyte adhesion to endothelial cells (126,127). Macca Root Powder ● Supports female hormonal health via increased sex drive, improved post-menopausal symptoms, and improved sexual desire (13). ● Increases luteinizing hormone (LH) production and reduced severity of menstruation (13). ● Increases sperm count in males via androgenic mechanisms associated with free testosterone increase (13). Tongkat Ali ● Reduces stress hormones (cortisol), increases free testosterone, enhances mood, and supports sexual function (132). Saw Palmetto ● Supports prostate health, cardiovascular health, and increased hair growth (133,134). ● Supports prostate health via anti-androgenic and anti-inflammatory effects resulting in reduced Benign prostatic hyperplasia (134). L-Arginine ● Natural vasodilator precursor to increased nitric oxide levels (1). ● Supports immune function by maturation of the T cell (immune cell) receptor zeta (TCR) (2). ● Improves exercise performance via increased stroke volume (blood flow) and increased nutrient delivery to exercising muscle (3). ● Reduces arterial blood pressure, insulin resistance, and supports fat lipolysis (fat burning) (4). Panax Ginseng ● Apoptogenic herb that supports antioxidant function, cognitive function, increased muscle mass, combats inflammation, stabilizes blood pressure, enhances sexual health, and enhances endurance performance (136). ● Combats inflammation via inhibition of hydroxyl radical(inflammation) and lipid peroxidation (136). ● Supports endurance performance by enhancing mitochondrial energy output during exercise (136). Sarsaparilla Root ● Supports Antioxidant activity, antimicrobial activity, immune system activity, and skin health (140). ● Supports skin health by inhibiting oxidative damage and skin-aging factor via mitogen-activated protein kinase signaling pathways (141). ● Supports immune health and antioxidant activity by increasing l-glutathione levels (master antioxidant) and enhanced free radical scavenging capabilities (141). Pumpkin Seed Extract ● Supports urinary health, and immune function (175). ● Substantial improvement in BPH/LUTS. The observed symptom relief is accompanied by a clinically significant improvement in IPSS-related (175). Muira Puma Extract ● Supports sexual vitality in males and females, reduces stress, and increases blood flow to sexual organs (135). Oat Straw ● May support antioxidant function and cardiovascular health (185). Nettle ● Supports blood sugar regulation and urinary health. Cayenne Pepper ● Combats diarrhea, cramps, and muscle inflammation (176). ● Decreases muscle soreness and increases muscle strength (177). Astragalus Root ● Supports immune health, improves blood sugar regulation, and reduces inflammatory markers seen in gastrointestinal chronic diseases (16). ● Improves insulin resistance by reduction of inflammatory blood markers, increasing glucose uptake by exercising skeletal muscle, and improving glycogen (storage form of carbohydrates) synthesis (17). Catuba Bark ● May support antioxidant function. Licorice Root ● Supports anti-inflammatory, anti-allergenic, and antimicrobial properties (178). Tribulus Terrestris ● Supports sexual function, increased testosterone, cardiovascular health, supports healthy urinary tract function, supports athletic performance, and aids as a neuroprotective agent (137,138). ● Supports sexual health, via activating aphrodisiacs, increased spermatogenesis, sperm motility, increased free testosterone, and increase of androgenic (hormone) action via the activation of endogenous testosterone production (137,138). ● Supports cardiovascular health via decreased arterial inflammation levels of tumor necrosis factor (TNF)-α and interleukin (IL)-6 (137,138). ● Supports neuroprotective properties via protection of neuron injury, and cerebral ischemia-reperfusion by suppressing brain inflammatory markers (NF-κB, TNF-α and IL-1β) (137,138). Oyster Extract ● Reduces inflammation and supports joint health (178,179). ● Supports immune health via reduced generation of intracellular reactive oxygen species and increased levels of l-glutathione (master antioxidant) in macrophages (immune cells) (178,179). Boron ● Supports increased bone mineral density, muscle function, hormonal balance, and immune function (180). Proper Use of This Supplement Suggested Use: Take three (3) capsules before bedtime. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. Uses high-quality herbs, nootropics, vitamins, and minerals in an effective and efficaciously dosed formula. 2. Uses cheap sources of herbs, nootropics, vitamins, and minerals that contain high amounts of fillers and heavy metals. Sources 1.Sureda, A., & Pons, A. (2012). Arginine and citrulline supplementation in sports and exercise: ergogenic nutrients?. Medicine and sport science, 59, 18–28. https://doi.org/10.1159/000341937 2.Szefel, J., Danielak, A., & Kruszewski, W. J. (2019). Metabolic pathways of L-arginine and therapeutic consequences in tumors. Advances in medical sciences, 64(1), 104–110. https://doi.org/10.1016/j.advms.2018.08.018 3.Rodrigues-Krause, J., Krause, M., Rocha, I., Umpierre, D., & Fayh, A. (2018). Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis. Nutrients, 11(1), 15. https://doi.org/10.3390/nu11010015 4.Hu, S., Han, M., Rezaei, A., Li, D., Wu, G., & Ma, X. (2017). L-Arginine Modulates Glucose and Lipid Metabolism in Obesity and Diabetes. Current protein & peptide science, 18(6), 599–608. https://doi.org/10.2174/1389203717666160627074017 Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x 13.Dording, C. M., Schettler, P. J., Dalton, E. D., Parkin, S. R., Walker, R. S., Fehling, K. B., Fava, M., & Mischoulon, D. (2015). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evidence-based complementary and alternative medicine : eCAM, 2015, 949036. https://doi.org/10.1155/2015/949036 Auyeung, K. K., Han, Q. B., & Ko, J. K. (2016). Astragalus membranaceus: A Review of its Protection Against Inflammation and Gastrointestinal Cancers. The American journal of Chinese medicine, 44(1), 1–22. https://doi.org/10.1142/S0192415X16500014 Zhang, Z., Zhang, L., & Xu, H. (2019). Effect of Astragalus polysaccharide in treatment of diabetes mellitus: a narrative review. Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 39(1), 133–138. Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.00734 Rehman, S. U., Choe, K., & Yoo, H. H. (2016). Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules (Basel, Switzerland), 21(3), 331. https://doi.org/10.3390/molecules21030331 Evron, E., Juhasz, M., Babadjouni, A., & Mesinkovska, N. A. (2020). Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia. Skin appendage disorders, 6(6), 329–337. https://doi.org/10.1159/000509905 Kwon Y. (2019). Use of saw palmetto (Serenoa repens) extract for benign prostatic hyperplasia. Food science and biotechnology, 28(6), 1599–1606. https://doi.org/10.1007/s10068-019-00605-9 Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells. Nitric oxide : biology and chemistry, 76, 81–86. https://doi.org/10.1016/j.niox.2018.03.010 Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Saudan, C., Baume, N., Emery, C., Strahm, E., & Saugy, M. (2008). Short term impact of Tribulus terrestris intake on doping control analysis of endogenous steroids. Forensic science international, 178(1), e7–e10. https://doi.org/10.1016/j.forsciint.2008.01.003 Das, S., & Bisht, S. S. (2013). The bioactive and therapeutic potential of Hemidesmus indicus R. Br. (Indian Sarsaparilla) root. Phytotherapy research : PTR, 27(6), 791–801. https://doi.org/10.1002/ptr.4788 She, T., Qu, L., Wang, L., Yang, X., Xu, S., Feng, J., Gao, Y., Zhao, C., Han, Y., Cai, S., & Shou, C. (2015). Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy via Redox-Dependent ERK1/2 Pathway. Cancer prevention research (Philadelphia, Pa.), 8(5), 464–474. https://doi.org/10.1158/1940-6207.CAPR-14-0372 Hsu, Y. J., Huang, W. C., Chiu, C. C., Liu, Y. L., Chiu, W. C., Chiu, C. H., Chiu, Y. S., & Huang, C. C. (2016). Capsaicin Supplementation Reduces Physical Fatigue and Improves Exercise Performance in Mice. Nutrients, 8(10), 648. https://doi.org/10.3390/nu8100648 Eichner E. R. (2016). Fighting Muscle Cramps With Two Spices and One Hot Fruit. Current sports medicine reports, 15(5), 304–305. https://doi.org/10.1249/JSR.0000000000000298 Lee, S. Y., Kim, H. J., & Han, J. S. (2013). Anti-inflammatory Effect of Oyster Shell Extract in LPS-stimulated Raw 264.7 Cells. Preventive nutrition and food science, 18(1), 23–29. https://doi.org/10.3746/pnf.2013.18.1.023 Jeong, J. W., Choi, S. H., Han, M. H., Kim, G. Y., Park, C., Hong, S. H., Lee, B. J., Park, E. K., Kim, S. O., Leem, S. H., Jeon, Y. J., & Choi, Y. H. (2019). Protective Effects of Fermented Oyster Extract against RANKL-Induced Osteoclastogenesis through Scavenging ROS Generation in RAW 264.7 Cells. International journal of molecular sciences, 20(6), 1439. https://doi.org/10.3390/ijms20061439 Khaliq, H., Juming, Z., & Ke-Mei, P. (2018). The Physiological Role of Boron on Health. Biological trace element research, 186(1), 31–51. https://doi.org/10.1007/s12011-018-1284-3 * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$29.99
GENESIS DRIVE FOR WOMEN
A blend of natural herbs and vitamins that are specifically formulated to naturally help enhance female libido levels, stamina, sexual stimulation, and enjoyment, by helping the body increase natural lubrication, for a more heighten sexual response. Serving Size: 2 Capsules Servings Per Container: 30 Formula Purposes & Benefits Genesis Blends Drive For Women is formulated to increase sexual arousal, sexual function, positive mood, reduced cortisol, increased nitric oxide production, increased muscle mass, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high-quality ingredients. Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Vitamin A (beta carotene) ● Supports vision health, skin health, immune health, and increases antioxidant support (182, 183). ● Supports antioxidant function via decreased inflammatory cytokines (inflammation), decreased reactive oxygen species, and increased l-glutathione production (master antioxidant) (182, 183). ● Supports visual health via increased amounts of plasma vitamin A in macular (eye) tissues (182, 183). Vitamin B1 (Thiamine) ● Supports aerobic energy metabolism (oxidative phosphorylation), cell growth, optimal neuronal conduction (nerve impulses), and cardiovascular health (94). ● Supports cardiovascular function and aids as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95). Vitamin B2 (Riboflavin) ● Supports conversion and activation of other B vitamins, red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93). Vitamin B3 (Niacin) ● Major B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9). ● Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9). ● Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9). ● Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9). ● Prevents pathologies(diseases) such as Pellagra and reduces prevalence of nervous anorexia, cancer, and crohn's disease (10, 11). ● Supports sensitization of tumors to radiation via apoptosis (cell death) cascade of tumor mass and improves oxygen delivery to malignant tissues (cancer cells) (12). ● Supports cognitive health by reducing age-related decline of NAD+, increasing quinolinic acid and reducing neuroinflammation (9). ● Increased niacin associated NAD+ levels have been shown to increase neurotransmission, learning and memory (9). ● Niacin reduces the prevalence of neurodegenerative pathologies by preventing mitochondrial dysfunction (9). Vitamin B6 ● Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). ● Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). ● Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). ● May support blood sugar regulation in women with gestational diabetes (40). ● cofactor for enzymes involved in DNA metabolism (40). Vitamin B12 ● Supports proper DNA synthesis, folate cycle function, energy production, cognitive function, and immune health (51,53). ● Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress (51). ● May prevent vitamin b-12 deficiency diseases such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis (53). Zinc ● Supports immune function, skin health, cognitive function, and vision (172,173). ● Supports stimulation of the innate and adaptive immune system (172,173). ● Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173). ● Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173). L-Tyrosine ● Supports memory, cognitive flexibility, the executive function of the brain, and convergent thinking (60). ● A precursor to dopamine and is vital for dopamine synthesis in the brain (60). ● Supports cognitive function in individuals with high amounts of stress and anxiety (60,61). ● Increases dopamine levels in highly stressed individuals (60). Maca Root Powder ● Supports female hormonal health via increased sex drive, improved post-menopausal symptoms, and improved sexual desire (13). ● Increases luteinizing hormone (LH) production and reduced severity of menstruation (13). ● Increases sperm count in males via androgenic mechanisms associated with free testosterone increase (13). Munica Pruriens ● Supports blood sugar regulation, sexual enhancement, aids an anti-inflammatory agent, combats neurodegenerative disease, and supports antimicrobial activity (128). ● Supports anti-aging, rheumatoid, arthritis, diabetes, male infertility, and nervous disorders (128). ● Supports male sexual health via increased sperm motility and increased free testosterone (128). ● Combats neurodegenerative disease via stimulation of dopaminergic neurons (129). ● Supports blood sugar health via reduced blood glucose levels, improved insulin transport, and lowered H1AC levels (130). Muira Puama Root Powder ● Supports sexual vitality in males and females, reduces stress, and increases blood flow to sexual organs (135). L-Arginine ● Natural vasodilator precursor to increased nitric oxide levels (1). ● Supports immune function by the maturation of the T cell (immune cell) receptor zeta (TCR) (2.) ● Improves exercise performance via increased stroke volume (blood flow) and increased nutrient delivery to exercising muscle. (3). ● Reduces arterial blood pressure, insulin resistance, and supports fat lipolysis (fat burning) (4). Panax Ginseng ● An adaptogenic herb that supports antioxidant function, cognitive function, increased muscle mass, combats inflammation, stabilizes blood pressure, enhances sexual health, and enhances endurance performance (136). ● Combats inflammation via inhibition of hydroxyl radical(inflammation) and lipid peroxidation (136). ● Supports endurance performance by enhancing mitochondrial energy output during exercise (136). Epimedium/Horny Goat Weed ● Supports increased sexual drive, increased testosterone, reduced progression of atherosclerosis, increased nitric oxide levels, and reduced arterial (blood vessel) inflammation levels (126,127). ● Reduces arterial inflammation via reduction of free-radical-induced peroxidation in erythrocytes, and increased nitric oxide levels (126,127). ● Supports arterial health (health of blood vessels) via attenuating DNA damage, correcting endothelial dysfunction (126,127). ● Represses macrophage-derived foam cell formation, inhibiting platelet activation, and reduces oxLDL-induced monocyte adhesion to endothelial cells (126,127). Dong Quai ● Supports menstrual health in women. Tribulus Terrestris ● Supports sexual function, increased testosterone, cardiovascular health, supports healthy urinary tract function, supports athletic performance, and aids as a neuroprotective agent (137,138). ● Supports sexual health, via activating aphrodisiacs, increased spermatogenesis, sperm motility, increased free testosterone, and increase of androgenic (hormone) action via the activation of endogenous testosterone production (137,138). ● Supports cardiovascular health via decreased arterial inflammation levels of tumor necrosis factor (TNF)-α and interleukin (IL)-6 (137,138). ● Supports neuroprotective properties via protection of neuron injury, and cerebral ischemia-reperfusion by suppressing brain inflammatory markers (NF-κB, TNF-α and IL-1β) (137,138). Damiana ● Supports enhanced sexual function, reduced menopausal symptoms, reduced stress, and improved mood (139). ● Supports sexual health via regulation of the natural balance between androgens and estrogens in both men and women (139). Ashwagandha ● Supports cardiovascular, hormonal, immune, healthy weight loss, mood, and optimized sleep (82,83). ● Reduces stress hormone cortisol resulting in improved body composition, sex hormone profile, and mood (82,83). ● Improves exercise performance via increased V02 max, muscular endurance, muscle hypertrophy (muscle growth), and decreased muscular fatigue (83). ● Improves quality of sleep by enhancing sleep recovery, reducing plasma cortisol concentrations, and enhancing REM sleep cycles (83). ● Supports hormonal and immune health via reduced production of inflammatory molecules (reactive oxygen species) and simultaneous increases in sex hormones (84). Ginger ● Supports immune health, reduced blood pressure, digestive health, blood sugar regulation, and sexual health in men (110). ● Supports immune health via enhanced antioxidant, antimicrobial, and anti-inflammatory properties (110). ● Supports sex hormone health via decreased oxidative stress, increased luteinizing hormone (LH) production, reduced oxidative stress, reduced lipid peroxidation, enhanced activity antioxidant enzymes, increased blood flow, and recycling of testosterone receptors (110). Sarsaparilla root ● Supports Antioxidant activity, antimicrobial activity, immune system activity, and skin health (140). ● Supports skin health by inhibiting oxidative damage and skin-aging factor via mitogen-activated protein kinase signaling pathways (141). ● Supports immune health and antioxidant activity by increasing l-glutathione levels (master antioxidant) and enhanced free radical scavenging capabilities (141). Asparagus ● Supports immune health, enhances cognitive function, and combats neurodegenerative disease Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules once a day. For best results, light exercise and a sensible diet are recommended. Use this product for no less than 8 weeks for maximum results. Do not exceed 4 capsules a day. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. High-quality turmeric and ginger in an effective and efficaciously dosed formula 2. Uses cheap sources of turmeric and ginger that contain high amounts of fillers and heavy metals. Sources 1.Sureda, A., & Pons, A. (2012). Arginine and citrulline supplementation in sports and exercise: ergogenic nutrients?. Medicine and sport science, 59, 18–28. https://doi.org/10.1159/000341937 2.Szefel, J., Danielak, A., & Kruszewski, W. J. (2019). Metabolic pathways of L-arginine and therapeutic consequences in tumors. Advances in medical sciences, 64(1), 104–110. https://doi.org/10.1016/j.advms.2018.08.018 3.Rodrigues-Krause, J., Krause, M., Rocha, I., Umpierre, D., & Fayh, A. (2018). Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis. Nutrients, 11(1), 15. https://doi.org/10.3390/nu11010015 4.Hu, S., Han, M., Rezaei, A., Li, D., Wu, G., & Ma, X. (2017). L-Arginine Modulates Glucose and Lipid Metabolism in Obesity and Diabetes. Current protein & peptide science, 18(6), 599–608. https://doi.org/10.2174/1389203717666160627074017 9.Gasperi, V., Sibilano, M., Savini, I., & Catani, M. V. (2019). Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications. International journal of molecular sciences, 20(4), 974. https://doi.org/10.3390/ijms20040974 10.Gentilcore D. (2016). Louis Sambon and the Clash of Pellagra Etiologies in Italy and the United States, 1905-14. Journal of the history of medicine and allied sciences, 71(1), 19–42. https://doi.org/10.1093/jhmas/jrv002 11.Kirkland J. B. (2009). Niacin status and treatment-related leukemogenesis. Molecular cancer therapeutics, 8(4), 725–732. https://doi.org/10.1158/1535-7163.MCT-09-0042 12.Hoskin, P., Rojas, A., & Saunders, M. (2009). Accelerated radiotherapy, carbogen, and nicotinamide (ARCON) in the treatment of advanced bladder cancer: mature results of a Phase II nonrandomized study. International journal of radiation oncology, biology, physics, 73(5), 1425–1431. https://doi.org/10.1016/j.ijrobp.2008.06.1950 Ueland, P. M., McCann, A., Midttun, Ø., & Ulvik, A. (2017). Inflammation, vitamin B6 and related pathways. Molecular aspects of medicine, 53, 10–27. https://doi.org/10.1016/j.mam.2016.08.001 Bird R. P. (2018). The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis. Advances in food and nutrition research, 83, 151–194. https://doi.org/10.1016/bs.afnr.2017.11.004 Mascolo, E., & Vernì, F. (2020). Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms. International journal of molecular sciences, 21(10), 3669. https://doi.org/10.3390/ijms21103669 van de Lagemaat, E. E., de Groot, L., & van den Heuvel, E. (2019). Vitamin B12in Relation to Oxidative Stress: A Systematic Review. Nutrients, 11(2), 482. https://doi.org/10.3390/nu11020482 Romain, M., Sviri, S., Linton, D. M., Stav, I., & van Heerden, P. V. (2016). The role of Vitamin B12 in the critically ill--a review. Anaesthesia and intensive care, 44(4), 447–452. https://doi.org/10.1177/0310057X1604400410 Shipton, M. J., & Thachil, J. (2015). Vitamin B12 deficiency - A 21st century perspective . Clinical medicine (London, England), 15(2), 145–150. https://doi.org/10.7861/clinmedicine.15-2-145 Hoffer, L. J., Sher, K., Saboohi, F., Bernier, P., MacNamara, E. M., & Rinzler, D. (2003). N-acetyl-L-tyrosine as a tyrosine source in adult parenteral nutrition. JPEN. Journal of parenteral and enteral nutrition, 27(6), 419–422. https://doi.org/10.1177/0148607103027006419 Ipson, B. R., & Fisher, A. L. (2016). Roles of the tyrosine isomers meta-tyrosine and ortho-tyrosine in oxidative stress. Ageing research reviews, 27, 93–107. https://doi.org/10.1016/j.arr.2016.03.005 Langade, D., Kanchi, S., Salve, J., Debnath, K., & Ambegaokar, D. (2019). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus, 11(9), e5797. https://doi.org/10.7759/cureus.5797 Bonilla, D. A., Moreno, Y., Gho, C., Petro, J. L., Odriozola-Martínez, A., & Kreider, R. B. (2021). Effects of Ashwagandha (Withania somnifera) on Physical Performance: Systematic Review and Bayesian Meta-Analysis. Journal of functional morphology and kinesiology, 6(1), 20. https://doi.org/10.3390/jfmk6010020 Thakur, K., Tomar, S. K., Singh, A. K., Mandal, S., & Arora, S. (2017). Riboflavin and health: A review of recent human research. Critical reviews in food science and nutrition, 57(17), 3650–3660. https://doi.org/10.1080/10408398.2016.1145104 Suwannasom, N., Kao, I., Pruß, A., Georgieva, R., & Bäumler, H. (2020). Riboflavin: The Health Benefits of a Forgotten Natural Vitamin. International journal of molecular sciences, 21(3), 950. https://doi.org/10.3390/ijms21030950 DiNicolantonio, J. J., Niazi, A. K., Lavie, C. J., O'Keefe, J. H., & Ventura, H. O. (2013). Thiamine supplementation for the treatment of heart failure: a review of the literature. Congestive heart failure (Greenwich, Conn.), 19(4), 214–222. https://doi.org/10.1111/chf.12037 Saedisomeolia, A., & Ashoori, M. (2018).Thiamine in Human Health: A Review of Current Evidences. Advances in food and nutrition research, 83, 57–81. https://doi.org/10.1016/bs.afnr.2017.11.002 Hasani, H., Arab, A., Hadi, A., Pourmasoumi, M., Ghavami, A., & Miraghajani, M. (2019). Does ginger supplementation lower blood pressure? A systematic review and meta-analysis of clinical trials. Phytotherapy research : PTR, 33(6), 1639–1647. https://doi.org/10.1002/ptr.6362 Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.00734 13.Dording, C. M., Schettler, P. J., Dalton, E. D., Parkin, S. R., Walker, R. S., Fehling, K. B., Fava, M., & Mischoulon, D. (2015). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evidence-based complementary and alternative medicine : eCAM, 2015, 949036. https://doi.org/10.1155/2015/949036 Pathania, R., Chawla, P., Khan, H., Kaushik, R., & Khan, M. A. (2020). An assessment of potential nutritive and medicinal properties of Mucuna pruriens: a natural food legume. 3 Biotech, 10(6), 261. https://doi.org/10.1007/s13205-020-02253-x Rakesh B, Praveen N (2020) Chapter-10 biotechnological approaches for the production of l-DOPA: a novel and potent anti-Parkinson’s Drug from Mucuna pruriens (L.) DC. Chief Editor: 179 Majekodunmi, S. O., Oyagbemi, A. A., Umukoro, S., & Odeku, O. A. (2011). Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract. Asian Pacific journal of tropical medicine, 4(8), 632–636. https://doi.org/10.1016/S1995-7645(11)60161-2 Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells. Nitric oxide : biology and chemistry, 76, 81–86. https://doi.org/10.1016/j.niox.2018.03.010 Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Saudan, C., Baume, N., Emery, C., Strahm, E., & Saugy, M. (2008). Short term impact of Tribulus terrestris intake on doping control analysis of endogenous steroids. Forensic science international, 178(1), e7–e10. https://doi.org/10.1016/j.forsciint.2008.01.003 Palacios, S., Soler, E., Ramírez, M., Lilue, M., Khorsandi, D., & Losa, F. (2019). Effect of a multi-ingredient based food supplement on sexual function in women with low sexual desire. BMC women's health, 19(1), 58. https://doi.org/10.1186/s12905-019-0755-9 Das, S., & Bisht, S. S. (2013). The bioactive and therapeutic potential of Hemidesmus indicus R. Br. (Indian Sarsaparilla) root. Phytotherapy research : PTR, 27(6), 791–801. https://doi.org/10.1002/ptr.4788 She, T., Qu, L., Wang, L., Yang, X., Xu, S., Feng, J., Gao, Y., Zhao, C., Han, Y., Cai, S., & Shou, C. (2015). Sarsaparilla (Smilax Glabra Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy via Redox-Dependent ERK1/2 Pathway. Cancer prevention research (Philadelphia, Pa.), 8(5), 464–474. https://doi.org/10.1158/1940-6207.CAPR-14-0372 Majumdar, S., Gupta, S., Prajapati, S. K., & Krishnamurthy, S. (2021). Neuro-nutraceutical potential of Asparagus racemosus: A review. Neurochemistry international, 145, 105013. https://doi.org/10.1016/j.neuint.2021.105013 Maywald, M., Wessels, I., & Rink, L. (2017). Zinc Signals and Immunity. International journal of molecular sciences, 18(10), 2222. https://doi.org/10.3390/ijms18102222 Wessels, I., Rolles, B., & Rink, L. (2020). The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis. Frontiers in immunology, 11, 1712. https://doi.org/10.3389/fimmu.2020.01712 * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
$29.99
WOMEN'S DRIVE & ENHANCEMENT PACK: GENESIS ULTRA DAILY MULTIVITAMIN AND DRIVE FOR WOMEN
Save with the Genesis Blends bundle packs. The bundle includes Ultra Daily Multivitamin capsules and Drive for Women capsules.
$59.00
MEN'S DRIVE & ENHANCEMENT PACK: ULTRA DAILY VITAMIN, REVITALIZING FORMULA, ENHANCEMENT FORMULA, AND HORNY GOAT WEED
Save with the Genesis Blends bundle packs. The bundle includes Ultra Daily Vitamin, Revitalizing Formula, Male Enhancement Formula, and Horny Goat Weed.
$108.99
HORNY GOAT WEED BLEND
Formula Purposes & Benefits Horny Goat Weed blend is formulated to increase natural testosterone levels, sexual function, positive mood, reduced cortisol, increased nitric oxide production, increased muscle mass, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high quality Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards. Formula Ingredient Deck Benefits Of Each Ingredient Horny Goat Weed Supports increased sexual drive, increased testosterone, reduced progression of atherosclerosis, increased nitric oxide levels, and reduced arterial (blood vessel) inflammation levels (126,127). Reduces arterial inflammation via reduction of free-radical-induced peroxidation in erythrocytes, and increased nitric oxide levels (126,127). supports arterial health (health of blood vessels) via attenuating DNA damage, correcting endothelial dysfunction (126,127). represses macrophage-derived foam cell formation, inhibiting platelet activation, and reduces oxLDL-induced monocyte adhesion to endothelial cells (126,127). Macca Root Powder Supports female hormonal health via increased sex drive, improved post-menopausal symptoms, and improved sexual desire (13). Increases luteinizing hormone (LH) production and reduced severity of menstruation (13). Increases sperm count in males via androgenic mechanisms associated with free testosterone increase (13). Munica Pruriens Supports blood sugar regulation, sexual enhancement, aids an anti-inflammatory agent, combats neurodegenerative disease, and supports antimicrobial activity (128). Supports anti-aging, rheumatoid, arthritis, diabetes, male infertility, and nervous disorders (128). Supports male sexual health via increased sperm motility and increased free testosterone (128). Combats neurodegenerative disease via stimulation of dopaminergic neurons (129). Supports blood sugar health via reduced blood glucose levels, improved insulin transport, and lowered H1AC levels (130). Polypodium Vulgare Powder Supports wound healing and enhances antioxidant support (130). Support would healing via regenerating the epidermis and increasing vascularization (131). Tongkat Ali Reduces stress hormones (cortisol), increases free testosterone, enhances mood, and supports sexual function (132). Saw Palmetto Supports prostate health, cardiovascular health, and increased hair growth (133,134). Supports prostate health via anti-androgenic and anti-inflammatory effects resulting in reduced Benign prostatic hyperplasia (134). Muira Puama Root Powder Supports sexual vitality in males and females, reduces stress, and increases blood flow to sexual organs (135). L-Arginine Natural vasodilator precursor to increased nitric oxide levels (1). Supports immune function by the maturation of the T cell (immune cell) receptor zeta (TCR) (2). Improves exercise performance via increased stroke volume (blood flow) and increased nutrient delivery to exercising muscle. (3). Reduces arterial blood pressure, insulin resistance, and supports fat lipolysis (fat burning) (4). Panax Ginseng An adaptogenic herb that supports antioxidant function, cognitive function, increased muscle mass, combats inflammation, stabilizes blood pressure, enhances sexual health, and enhances endurance performance (136). Combats inflammation via inhibition of hydroxyl radical(inflammation) and lipid peroxidation (136). Supports endurance performance by enhancing mitochondrial energy output during exercise (136). Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules once a day. For best results, take 20-30 minutes before a meal with an 8 oz glass of water, or as directed by your health care professional. Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. High-quality herbs and nootropics in an effective and efficaciously dosed formula. 2. Uses cheap sources of herbs and nootropics that contain high amounts of fillers and heavy metals. Sources 1.Sureda, A., & Pons, A. (2012). Arginine and citrulline supplementation in sports and exercise: ergogenic nutrients?. Medicine and sport science, 59, 18–28. https://doi.org/10.1159/000341937 2.Szefel, J., Danielak, A., & Kruszewski, W. J. (2019). Metabolic pathways of L-arginine and therapeutic consequences in tumors. Advances in medical sciences, 64(1), 104–110. https://doi.org/10.1016/j.advms.2018.08.018 3.Rodrigues-Krause, J., Krause, M., Rocha, I., Umpierre, D., & Fayh, A. (2018). Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis. Nutrients, 11(1), 15. https://doi.org/10.3390/nu11010015 4.Hu, S., Han, M., Rezaei, A., Li, D., Wu, G., & Ma, X. (2017). L-Arginine Modulates Glucose and Lipid Metabolism in Obesity and Diabetes. Current protein & peptide science, 18(6), 599–608. https://doi.org/10.2174/1389203717666160627074017 Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.0073413.Dording, C. M., Schettler, P. J., Dalton, E. D., Parkin, S. R., Walker, R. S., Fehling, K. B., Fava, M., & Mischoulon, D. (2015). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evidence-based complementary and alternative medicine : eCAM, 2015, 949036. https://doi.org/10.1155/2015/949036Pathania, R., Chawla, P., Khan, H., Kaushik, R., & Khan, M. A. (2020). An assessment of potential nutritive and medicinal properties of Mucuna pruriens: a natural food legume. 3 Biotech, 10(6), 261. https://doi.org/10.1007/s13205-020-02253-x Rakesh B, Praveen N (2020) Chapter-10 biotechnological approaches for the production of l-DOPA: a novel and potent anti-Parkinson’s Drug from Mucuna pruriens (L.) DC. Chief Editor: 179 Majekodunmi, S. O., Oyagbemi, A. A., Umukoro, S., & Odeku, O. A. (2011). Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract. Asian Pacific journal of tropical medicine, 4(8), 632–636. https://doi.org/10.1016/S1995-7645(11)60161-2 Batur, S., Ayla, S., Sakul, A. A., Okur, M. E., Karadag, A. E., Daylan, B., Ozdemir, E. M., Kepil, N., & Gunal, M. Y. (2020). An Alternative Approach Wound Healing Field with Polypodium Vulgare. Medeniyet medical journal, 35(4), 315–323. https://doi.org/10.5222/MMJ.2020.89983 Rehman, S. U., Choe, K., & Yoo, H. H. (2016). Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules (Basel, Switzerland), 21(3), 331. https://doi.org/10.3390/molecules21030331 Evron, E., Juhasz, M., Babadjouni, A., & Mesinkovska, N. A. (2020). Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia. Skin appendage disorders, 6(6), 329–337. https://doi.org/10.1159/000509905 Kwon Y. (2019). Use of saw palmetto (Serenoa repens) extract for benign prostatic hyperplasia. Food science and biotechnology, 28(6), 1599–1606. https://doi.org/10.1007/s10068-019-00605-9 Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells. Nitric oxide : biology and chemistry, 76, 81–86. https://doi.org/10.1016/j.niox.2018.03.010 Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Serving Size: 2 Capsules;Capsules Per Container: 60;Bottle Color: White;Bottle Size: 175cc;Lid Color: White * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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