Home page

  Formula Purposes & Benefits B-12 drops is formulated to support increased energy, cardiovascular health, energy metabolism, digestive health, antioxidant support, immune health, and cognitive function. Our product is synthesized utilizing the latest scientific research and formulated with high quality ingredients. Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards.   Formula Ingredient Deck Benefits Of Each Ingredient  Vitamin B-12 Aids as an antioxidant via direct scavenging of reactive oxygen species (inflammation), preserving l-glutathione levels (master antioxidant), and reducing oxidative stress (51). May prevent vitamin B-12 deficiency diseases such as anemia, neurodegenerative disease, cardiovascular disease, and osteoporosis (53). Vitamin B6 Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). May support blood sugar regulation in women with gestational diabetes (40). Cofactor for enzymes involved in DNA metabolism (40). Vitamin B5 Supports energy production, cell growth, cell repair, cognitive function, increased hippocampal volume (memory), and optimized bioenergetics (burning of carbohydrates, fat, and protein) (96). Vitamin B2 Supports conversion and activation of other B vitamins, red blood cell production and serves as a cofactor for both glucose and fat metabolism (energy production) (92,93). Vitamin B3 (Niacin) Major B vitamin that supports cardiovascular health by inhibiting hepatic(liver) triglyceride synthesis, reducing very-low-density lipoprotein (VLDL) secretion, and increasing HDL plasma concentrations (9). Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9). Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9). Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9). Prevents pathologies(diseases) such as Pellagra and reduces prevalence of nervous anorexia, cancer, and crohn's disease (10, 11). Supports sensitization of tumors to radiation via apoptosis (cell death) cascade of tumor mass and improves oxygen delivery to malignant tissues (cancer cells) (12). Supports cognitive health by reducing age-related decline of NAD+, increasing quinolinic acid and reducing neuroinflammation (9). Increased niacin associated NAD+ levels have been shown to increase neurotransmission, learning and memory (9). Niacin reduces the prevalence of neurodegenerative pathologies by preventing mitochondrial dysfunction (9). Proper Use of This Supplement Suggested Use:  Shake well before use. Adults, place one full dropper (1ml) in mouth. Vitamin B-12 complex is essential for maintenance of healthy nervous tissue. B Vitamins play a major role in energy metabolism for the body.   Our Formula Vs Other Formulas on the Market. 1. Uses third party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third party tested have been removed by FDA due to high levels of heavy metals. 2. Uses high quality nutraceuticals in an effective evidence based and efficaciously dosed formula. 2. Uses cheap sources of nutraceuticals that contain high amounts of fillers, heavy metals, and in formulated without evidence based dosages. Serving Size: 1 ml;Servings Per Bottle: 60;Bottle Color: Amber;Bottle Size: 2 oz (60 ml);Lid Color: Black * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.  

Read more less

Formula Purposes & Benefits Apple Cider Vinegar Capsules are synthesized to healthy cholesterol, blood sugar, immune health, digestive health, and increased fat burning. Our product is synthesized utilizing the latest scientific research and formulated with optimal ratios of branch chain amino acids to produce world class results. Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards.   Formula Ingredient Deck Benefits Of Each Ingredient Apple Cider Vinegar Supports healthy cholesterol, glucose, triglyceride, and hemoglobin A1C levels (28). Reduces total plasma cholesterol concentrations via increased stimulation of acid bile excretion (29). Supports immune health with high concentrations of flavonoids, gallic acid, catechins, and ferulic acid (29). Improves blood sugar regulation by increased glucose utilization, lipolysis (fat burning), reduced lipogenesis (fat storage), and suppressing hepatic (liver) synthesis of glucose (30). Proper Use of This Supplement Suggested Use:  As a dietary supplement, take two (2) capsules once a day. For best results take20-30 min before a meal, or as directed by your healthcare professional.   Our Formula Vs other formulas in the market. 1. Uses third party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third party tested have been removed by FDA due to high levels of heavy metals. 2. Uses vegetable capsulation with nontoxic ingredients. 2. Uses cheap fillers and toxic ingredients in capsulation. Sources: Kausar, S., Humayun, A., Ahmed, Z., Abbas, M., & Tahir, A. (2019). Effect of Apple Cider Vinegar on Glycemic Control, Hyperlipidemia and Control on Body Weight in Type 2 Diabetes Patients. International Journal of Medical Research and Health Sciences, 8, 59-74. Hadi, A., Pourmasoumi, M., Najafgholizadeh, A., Clark, C., & Esmaillzadeh, A. (2021). The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC complementary medicine and therapies, 21(1), 179. https://doi.org/10.1186/s12906-021-03351-w Petsiou, E. I., Mitrou, P. I., Raptis, S. A., & Dimitriadis, G. D. (2014). Effect and mechanisms of action of vinegar on glucose metabolism, lipid profile, and body weight. Nutrition reviews, 72(10), 651–661. https://doi.org/10.1111/nure.12125 Serving Size: 2 Capsules;Capsules Per Container: 60;Bottle Color: White;Bottle Size: 175cc;Lid Color: White   * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Read more less

Formula Purposes & Benefits Horny Goat Weed blend is formulated to increase natural testosterone levels, sexual function, positive mood, reduced cortisol, increased nitric oxide production, increased muscle mass, and improved exercise performance. Our product is synthesized utilizing the latest scientific research and formulated with high quality Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards.   Formula Ingredient Deck Benefits Of Each Ingredient  Horny Goat Weed Supports increased sexual drive, increased testosterone, reduced progression of atherosclerosis, increased nitric oxide levels, and reduced arterial (blood vessel) inflammation levels (126,127). Reduces arterial inflammation via reduction of free-radical-induced peroxidation in erythrocytes, and increased nitric oxide levels (126,127). supports arterial health (health of blood vessels) via attenuating DNA damage, correcting endothelial dysfunction (126,127). represses macrophage-derived foam cell formation, inhibiting platelet activation, and reduces oxLDL-induced monocyte adhesion to endothelial cells (126,127). Macca Root Powder Supports female hormonal health via increased sex drive, improved post-menopausal symptoms, and improved sexual desire (13). Increases luteinizing hormone (LH) production and reduced severity of menstruation (13). Increases sperm count in males via androgenic mechanisms associated with free testosterone increase (13). Munica Pruriens Supports blood sugar regulation, sexual enhancement, aids an anti-inflammatory agent, combats neurodegenerative disease, and supports antimicrobial activity (128). Supports anti-aging, rheumatoid, arthritis, diabetes, male infertility, and nervous disorders (128). Supports male sexual health via increased sperm motility and increased free testosterone (128). Combats neurodegenerative disease via stimulation of dopaminergic neurons (129). Supports blood sugar health via reduced blood glucose levels, improved insulin transport, and lowered H1AC levels (130). Polypodium Vulgare Powder Supports wound healing and enhances antioxidant support (130). Support would healing via regenerating the epidermis and increasing vascularization (131). Tongkat Ali Reduces stress hormones (cortisol), increases free testosterone, enhances mood, and supports sexual function (132). Saw Palmetto Supports prostate health, cardiovascular health, and increased hair growth (133,134). Supports prostate health via anti-androgenic and anti-inflammatory effects resulting in reduced Benign prostatic hyperplasia (134). Muira Puama Root Powder Supports sexual vitality in males and females, reduces stress, and increases blood flow to sexual organs (135). L-Arginine Natural vasodilator precursor to increased nitric oxide levels (1). Supports immune function by the maturation of the T cell (immune cell) receptor zeta (TCR) (2). Improves exercise performance via increased stroke volume (blood flow) and increased nutrient delivery to exercising muscle. (3). Reduces arterial blood pressure, insulin resistance, and supports fat lipolysis (fat burning) (4). Panax Ginseng An adaptogenic herb that supports antioxidant function, cognitive function, increased muscle mass, combats inflammation, stabilizes blood pressure, enhances sexual health, and enhances endurance performance (136). Combats inflammation via inhibition of hydroxyl radical(inflammation) and lipid peroxidation (136). Supports endurance performance by enhancing mitochondrial energy output during exercise (136). Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules once a day. For best results, take 20-30 minutes before a meal with an 8 oz glass of water, or as directed by your health care professional.   Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. High-quality herbs and nootropics in an effective and efficaciously dosed formula. 2. Uses cheap sources of herbs and nootropics that contain high amounts of fillers and heavy metals. Sources 1.Sureda, A., & Pons, A. (2012). Arginine and citrulline supplementation in sports and exercise: ergogenic nutrients?. Medicine and sport science, 59, 18–28. https://doi.org/10.1159/000341937 2.Szefel, J., Danielak, A., & Kruszewski, W. J. (2019). Metabolic pathways of L-arginine and therapeutic consequences in tumors. Advances in medical sciences, 64(1), 104–110. https://doi.org/10.1016/j.advms.2018.08.018 3.Rodrigues-Krause, J., Krause, M., Rocha, I., Umpierre, D., & Fayh, A. (2018). Association of l-Arginine Supplementation with Markers of Endothelial Function in Patients with Cardiovascular or Metabolic Disorders: A Systematic Review and Meta-Analysis. Nutrients, 11(1), 15. https://doi.org/10.3390/nu11010015 4.Hu, S., Han, M., Rezaei, A., Li, D., Wu, G., & Ma, X. (2017). L-Arginine Modulates Glucose and Lipid Metabolism in Obesity and Diabetes. Current protein & peptide science, 18(6), 599–608. https://doi.org/10.2174/1389203717666160627074017 Kuchakulla, M., Narasimman, M., Soni, Y., Leong, J. Y., Patel, P., & Ramasamy, R. (2021). A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. International journal of impotence research, 33(3), 311–317. https://doi.org/10.1038/s41443-020-0285-x Fang, J., & Zhang, Y. (2017). Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed. Frontiers in pharmacology, 8, 734. https://doi.org/10.3389/fphar.2017.0073413.Dording, C. M., Schettler, P. J., Dalton, E. D., Parkin, S. R., Walker, R. S., Fehling, K. B., Fava, M., & Mischoulon, D. (2015). A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evidence-based complementary and alternative medicine : eCAM, 2015, 949036. https://doi.org/10.1155/2015/949036Pathania, R., Chawla, P., Khan, H., Kaushik, R., & Khan, M. A. (2020). An assessment of potential nutritive and medicinal properties of Mucuna pruriens: a natural food legume. 3 Biotech, 10(6), 261. https://doi.org/10.1007/s13205-020-02253-x Rakesh B, Praveen N (2020) Chapter-10 biotechnological approaches for the production of l-DOPA: a novel and potent anti-Parkinson’s Drug from Mucuna pruriens (L.) DC. Chief Editor: 179 Majekodunmi, S. O., Oyagbemi, A. A., Umukoro, S., & Odeku, O. A. (2011). Evaluation of the anti-diabetic properties of Mucuna pruriens seed extract. Asian Pacific journal of tropical medicine, 4(8), 632–636. https://doi.org/10.1016/S1995-7645(11)60161-2 Batur, S., Ayla, S., Sakul, A. A., Okur, M. E., Karadag, A. E., Daylan, B., Ozdemir, E. M., Kepil, N., & Gunal, M. Y. (2020). An Alternative Approach Wound Healing Field with Polypodium Vulgare. Medeniyet medical journal, 35(4), 315–323. https://doi.org/10.5222/MMJ.2020.89983 Rehman, S. U., Choe, K., & Yoo, H. H. (2016). Review on a Traditional Herbal Medicine, Eurycoma longifolia Jack (Tongkat Ali): Its Traditional Uses, Chemistry, Evidence-Based Pharmacology and Toxicology. Molecules (Basel, Switzerland), 21(3), 331. https://doi.org/10.3390/molecules21030331 Evron, E., Juhasz, M., Babadjouni, A., & Mesinkovska, N. A. (2020). Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia. Skin appendage disorders, 6(6), 329–337. https://doi.org/10.1159/000509905 Kwon Y. (2019). Use of saw palmetto (Serenoa repens) extract for benign prostatic hyperplasia. Food science and biotechnology, 28(6), 1599–1606. https://doi.org/10.1007/s10068-019-00605-9 Ferrini, M. G., Garcia, E., Abraham, A., Artaza, J. N., Nguyen, S., & Rajfer, J. (2018). Effect of ginger, Paullinia cupana, muira puama and l- citrulline, singly or in combination, on modulation of the inducible nitric oxide- NO-cGMP pathway in rat penile smooth muscle cells. Nitric oxide : biology and chemistry, 76, 81–86. https://doi.org/10.1016/j.niox.2018.03.010 Sellami, M., Slimeni, O., Pokrywka, A., Kuvačić, G., D Hayes, L., Milic, M., & Padulo, J. (2018). Herbal medicine for sports: a review. Journal of the International Society of Sports Nutrition, 15, 14. https://doi.org/10.1186/s12970-018-0218-y Serving Size: 2 Capsules;Capsules Per Container: 60;Bottle Color: White;Bottle Size: 175cc;Lid Color: White * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Read more less

Formula Purposes & Benefits Prostate Support is formulated to support prostate health, antioxidant activity, energy, cognition, sexual function, mood, and cardiovascular health. Our product is synthesized utilizing the latest scientific research and formulated with high-quality ingredients. Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards.   Formula Ingredient Deck Benefits Of Each Ingredient  Vitamin E Supports immune function, cognitive health, cardiovascular health, and bone health (204,205,206,207,208) Supports immune health via neutralizing free radicals and reactive oxygen species, and increased T lymphocyte-mediated immune function (204). Supports cardiovascular health via reduced cholesterol (204). Supports cognitive function via reduced oxidative stress, inflammation, and DNA damage of neuronal tissues (208). Vitamin B6 Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39). Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40). May support blood sugar regulation in women with gestational diabetes (40). Cofactor for enzymes involved in DNA metabolism (40). Zinc Supports immune function, skin health, cognitive function, and vision (172,173). Supports stimulation of the innate and adaptive immune system (172,173). Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173). Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173). Copper Supports healthy blood sugar levels, energy metabolism and cholesterol management (143,144). Selenium Supports antioxidant function, cardiovascular health, cognitive function, thyroid health, and immune health (145, 146). Combats atherosclerosis, high cholesterol (hypercholesterolemia), and type 1 diabetes (147). Supports thyroid health via decreased circulating thyroid autoantibodies in patients with chronic autoimmune thyroiditis (AIT) (146). Increases the activity of selenoproteins that decrease reactive oxygen species (inflammation), increases natural killer activity, and increases glutathione (master antioxidant) levels (145,147). Saw Palmetto Supports prostate health, cardiovascular health, and increased hair growth (133,134). Supports prostate health via anti-androgenic and anti-inflammatory effects resulting in reduced Benign prostatic hyperplasia (134). Pygeum Africanum Supports healthy testosterone levels, improves prostate health, and reduces chronic inflammation (19). Red Raspberry A natural aromatic compound derived from raspberries enhancing fat oxidation(burning) and antioxidant protective mechanisms (20). Supports suppression of lipid accumulation (fat build-up) in adipocytes (fat cells) (21). Increases total antioxidant capacity by increasing enzymes associated with decreasing reactive oxygen species (superoxide dismutase) (22). Increases natural production of master antioxidant L-Glutathione (22). Graviola Supports antioxidant function, reduces inflammation, and aids an antimicrobial agent (186,187). Supports antioxidant function via 200 phytochemicals and high concentration of alkaloids (186,187). Combats inflammation via reduced inflammatory cytokines (markers of inflammation (186,187). Green Tea Extract Potent polyphenolic antioxidant that supports blood pressure, insulin sensitivity, and metabolic health (26). High in ECGC (epigallocatechin gallate) (26). ECGC is shown to reduce body fat mass, increase fat oxidation(burning) and increase caloric expenditure during exercise (25). Potent anti-inflammatory compound supporting glutathione production and inhibition of pro-inflammatory markers (cytokines) (26). Reduces oxidative stress (chronic inflammation in the body) (26). Cat’s Claw Supports respiratory health and combats neurodegenerative disease and inflammation (188). Supports respiratory health via reduced prevalence of respiratory infections entering lung cells (inhibition of ACE2 receptor protein docking) (182). Combats neurodegenerative disease via decreased accumulation of Brian plaques (beta-amyloid plaques) (189). Broccoli Extract Supports antioxidant activity due to the high content of polyphenols and flavonoids (antioxidants) (190). Tomato Extract/Lycopene Supports prostate health, cardiovascular support, antioxidant, anti-inflammatory, and chemoprotective properties against cancer (191,192, 193). Combats inflammation via scavenging of free radicals and reduced oxidative damage of DNA. (191,192,193). Combats carcinogenesis via carcinogen-metabolizing enzymes, apoptosis (cancer cell death), anti-proliferation, pro-differentiation, and anti-lipid peroxidation activities. (193). Inhibits phosphorylation of anti-oncogenes such as p53 and Rb. It also inhibits G0/G1 and S-phase of the cell cycle (193). Stinging Nettle Supports blood sugar regulation and urinary health. Maitake, Reishi, Shitake Supports immune health, antioxidant activity, balanced estrogen levels, antiviral support, antibacterial, reduced stress, improved exercise performance, and blood sugar regulation (194,195). Supports immune health via high concentrations of betagluxans which increase natural killer cell activity and t-cell-mediated immunity (194). Reduces the concentration of inflammatory cytokines IL-1α, IL-6, IL-10 and TNF-a (inflammation markers) in macrophages (immune cells) (194). High in the amino acid L-Ergothioneine (mainly found in mushrooms) that supports longevity, decreases chronic inflammation, and antioxidant activity (194). Quercetin Supports antioxidant, anti-inflammatory, immune system defense, reduced homocysteine (allergies), reduced triglycerides, and combats bacterial infections (114,115,116). Supports immune health via reduced c-reactive protein (major inflammatory biomarker), increased neutrophil chemotaxis, macrophage phagocytosis, NK cell lytic activity and mitogen-stimulated lymphocyte (white blood cell) proliferation (114). Supports antiviral and antibacterial activity in influenza A strains H1N1 (114). Juniper Supports urinary health via the decreased prevalence of urinary tract infections. Uva Ursi Supports urinary health via the decreased prevalence of urinary tract infections (196). Buchu Supports digestive and immune health. L-Alanine Supports blood sugar regulation, immune function, and recovery from exercise (197). Supports blood sugar regulation via increased glucose uptake into skeletal muscle and improved insulin sensitivity (197). L-Glycine Supports increased nitric oxide production, improved connective tissue health, improved sleep, and increased growth hormone production (198),199). Pumpkin Seed Supports urinary health, and immune function (175). Substantial improvement in BPH/LUTS. The observed symptom relief is accompanied by a clinically significant improvement in IPSS-related (175). Cayenne Pepper Combats diarrhea, cramps, and muscle inflammation (176). Decreases muscle soreness and increases muscle strength (177). Goldenseal Supports digestive health, antibacterial activity, and antioxidant support (201, 202). Supports antioxidant function via levels of berberine (alkaloid) (201,202). Marshmallow Supports digestive health and combats sore throats (200). Combats sore throats via increased protective film on the inflamed mucosa (inflamed throat tissue) (200). Parsley Supports immune health, antioxidant activity, and aids in the detoxification process (203,204). Proper Use of This Supplement Suggested Use: As a dietary supplement take two (2) veggie capsules once a day. For best results take two 20-30 minutes before a meal with an 8 oz glass of water, or as directed by your health care professional.    Our Formula Vs Other Formulas on the Market. 1. Uses third-party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third-party tested have been removed by FDA due to high levels of heavy metals. 2. Uses high-quality nutraceuticals in an effective evidence-based and efficaciously dosed formula. 2. Uses cheap sources of nutraceuticals that contain high amounts of fillers, heavy metals, and is formulated without evidence-based dosages. Sources  19.Salinas-Casado, J., Esteban-Fuertes, M., Carballido-Rodríguez, J., & Cozar-Olmo, J. M. (2020). Review of the experience and evidence of Pygeum africanum in urological practice. Revisión sobre la experiencia y evidencias del Pygeum africanum en Urología. Actas urologicas espanolas, 44(1), 9–13. https://doi.org/10.1016/j.acuro.2019.08.002 Lim, S. H., & Choi, C. I. (2021). Potentials of Raspberry Ketone as a Natural Antioxidant. Antioxidants (Basel, Switzerland), 10(3), 482. https://doi.org/10.3390/antiox10030482 Park K. S. (2010). Raspberry ketone increases both lipolysis and fatty acid oxidation in 3T3-L1 adipocytes. Planta medica, 76(15), 1654–1658. https://doi.org/10.1055/s-0030-1249860 Rothenberg, D. O., Zhou, C., & Zhang, L. (2018). A Review on the Weight-Loss Effects of Oxidized Tea Polyphenols. Molecules (Basel, Switzerland), 23(5), 1176. https://doi.org/10.3390/molecules23051176 Bogdanski, P., Suliburska, J., Szulinska, M., Stepien, M., Pupek-Musialik, D., & Jablecka, A. (2012). Green tea extract reduces blood pressure, inflammatory biomarkers, and oxidative stress and improves parameters associated with insulin resistance in obese, hypertensive patients. Nutrition research (New York, N.Y.), 32(6), 421–427. https://doi.org/10.1016/j.nutres.2012.05.007 Haidari, F., Samadi, M., Mohammadshahi, M., Jalali, M. T., & Engali, K. A. (2017). Energy restriction combined with green coffee bean extract affects serum adipocytokines and the body composition in obese women. Asia Pacific journal of clinical nutrition, 26(6), 1048–1054. https://doi.org/10.6133/apjcn.022017.03 Ueland, P. M., McCann, A., Midttun, Ø., & Ulvik, A. (2017). Inflammation, vitamin B6 and related pathways. Molecular aspects of medicine, 53, 10–27. https://doi.org/10.1016/j.mam.2016.08.001 Bird R. P. (2018). The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis. Advances in food and nutrition research, 83, 151–194. https://doi.org/10.1016/bs.afnr.2017.11.004 Mascolo, E., & Vernì, F. (2020). Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms. International journal of molecular sciences, 21(10), 3669. https://doi.org/10.3390/ijms21103669 Chilelli, N. C., Ragazzi, E., Valentini, R., Cosma, C., Ferraresso, S., Lapolla, A., & Sartore, G. (2016). Curcumin and Boswellia serrata Modulate the Glyco-Oxidative Status and Lipo-Oxidation in Master Athletes. Nutrients, 8(11), 745. https://doi.org/10.3390/nu8110745 Barzegar, A., & Moosavi-Movahedi, A. A. (2011). Intracellular ROS protection efficiency and free radical-scavenging activity of curcumin. PloS one, 6(10), e26012. https://doi.org/10.1371/journal.pone.0026012 Banik, U., Parasuraman, S., Adhikary, A. K., & Othman, N. H. (2017). Curcumin: the spicy modulator of breast carcinogenesis. Journal of experimental & clinical cancer research : CR, 36(1), 98. https://doi.org/10.1186/s13046-017-0566-5 Suhett, L. G., de Miranda Monteiro Santos, R., Silveira, B., Leal, A., de Brito, A., de Novaes, J. F., & Lucia, C. (2021). Effects of curcumin supplementation on sport and physical exercise: a systematic review. Critical reviews in food science and nutrition, 61(6), 946–958. https://doi.org/10.1080/10408398.2020.1749025 Pivari, F., Mingione, A., Brasacchio, C., & Soldati, L. (2019). Curcumin and Type 2 Diabetes Mellitus: Prevention and Treatment. Nutrients, 11(8), 1837. https://doi.org/10.3390/nu11081837 Ashtary-Larky, D., Rezaei Kelishadi, M., Bagheri, R., Moosavian, S. P., Wong, A., Davoodi, S. H., Khalili, P., Dutheil, F., Suzuki, K., & Asbaghi, O. (2021). The Effects of Nano-Curcumin Supplementation on Risk Factors for Cardiovascular Disease: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical Trials. Antioxidants (Basel, Switzerland), 10(7), 1015. https://doi.org/10.3390/antiox10071015 Evron, E., Juhasz, M., Babadjouni, A., & Mesinkovska, N. A. (2020). Natural Hair Supplement: Friend or Foe? Saw Palmetto, a Systematic Review in Alopecia. Skin appendage disorders, 6(6), 329–337. https://doi.org/10.1159/000509905 Kwon Y. (2019). Use of saw palmetto (Serenoa repens) extract for benign prostatic hyperplasia. Food science and biotechnology, 28(6), 1599–1606. https://doi.org/10.1007/s10068-019-00605-9 Gombart, A. F., Pierre, A., & Maggini, S. (2020). A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Nutrients, 12(1), 236. https://doi.org/10.3390/nu12010236 Heffernan, S. M., Horner, K., De Vito, G., & Conway, G. E. (2019). The Role of Mineral and Trace Element Supplementation in Exercise and Athletic Performance: A Systematic Review. Nutrients, 11(3), 696. https://doi.org/10.3390/nu11030696 Wang, N., Tan, H. Y., Li, S., Xu, Y., Guo, W., & Feng, Y. (2017). Supplementation of Micronutrient Selenium in Metabolic Diseases: Its Role as an Antioxidant. Oxidative medicine and cellular longevity, 2017, 7478523. https://doi.org/10.1155/2017/7478523 Wichman, J., Winther, K. H., Bonnema, S. J., & Hegedüs, L. (2016). Selenium Supplementation Significantly Reduces Thyroid Autoantibody Levels in Patients with Chronic Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis. Thyroid : official journal of the American Thyroid Association, 26(12), 1681–1692. https://doi.org/10.1089/thy.2016.0256 147.Benstoem, C., Goetzenich, A., Kraemer, S., Borosch, S., Manzanares, W., Hardy, G., & Stoppe, C. (2015). Selenium and its supplementation in cardiovascular disease--what do we know?. Nutrients, 7(5), 3094–3118. https://doi.org/10.3390/nu7053094 Maywald, M., Wessels, I., & Rink, L. (2017). Zinc Signals and Immunity. International journal of molecular sciences, 18(10), 2222. https://doi.org/10.3390/ijms18102222 Wessels, I., Rolles, B., & Rink, L. (2020). The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis. Frontiers in immunology, 11, 1712. https://doi.org/10.3389/fimmu.2020.01712 Vahlensieck, W., Theurer, C., Pfitzer, E., Patz, B., Banik, N., & Engelmann, U. (2015). Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urologia internationalis, 94(3), 286–295. https://doi.org/10.1159/000362903 Hsu, Y. J., Huang, W. C., Chiu, C. C., Liu, Y. L., Chiu, W. C., Chiu, C. H., Chiu, Y. S., & Huang, C. C. (2016). Capsaicin Supplementation Reduces Physical Fatigue and Improves Exercise Performance in Mice. Nutrients, 8(10), 648. https://doi.org/10.3390/nu8100648 Eichner E. R. (2016). Fighting Muscle Cramps With Two Spices and One Hot Fruit. Current sports medicine reports, 15(5), 304–305. https://doi.org/10.1249/JSR.0000000000000298 Ziaei R, Foshati S, Hadi A, Kermani MAH, Ghavami A, Clark CCT, Tarrahi MJ. The effect of nettle (Urtica dioica) supplementation on the glycemic control of patients with type 2 diabetes mellitus: A systematic review and meta-analysis. Phytother Res. 2020 Feb;34(2):282-294. doi: 10.1002/ptr.6535. Epub 2019 Dec 4. PMID: 31802554. Chen, P., Zhang, W., Wang, X., Zhao, K., Negi, D. S., Zhuo, L., Qi, M., Wang, X., & Zhang, X. (2015). Lycopene and Risk of Prostate Cancer: A Systematic Review and Meta-Analysis. Medicine, 94(33), e1260. https://doi.org/10.1097/MD.0000000000001260 Beynon, R. A., Richmond, R. C., Santos Ferreira, D. L., Ness, A. R., May, M., Smith, G. D., Vincent, E. E., Adams, C., Ala-Korpela, M., Würtz, P., Soidinsalo, S., Metcalfe, C., Donovan, J. L., Lane, A. J., Martin, R. M., ProtecT Study Group, & PRACTICAL consortium (2019). Investigating the effects of lycopene and green tea on the metabolome of men at risk of prostate cancer: The ProDiet randomised controlled trial. International journal of cancer, 144(8), 1918–1928. https://doi.org/10.1002/ijc.31929 Shanbhag V. K. (2016). Lycopene in cancer therapy. Journal of pharmacy & bioallied sciences, 8(2), 170–171. https://doi.org/10.4103/0975-7406.171740 Hetland G, Tangen JM, Mahmood F, Mirlashari MR, Nissen-Meyer LSH, Nentwich I, Therkelsen SP, Tjønnfjord GE, Johnson E. Antitumor, Anti-Inflammatory and Antiallergic Effects of Agaricus blazei Mushroom Extract and the Related Medicinal Basidiomycetes Mushrooms, Hericium erinaceus and Grifolafrondosa: A Review of Preclinical and Clinical Studies. Nutrients. 2020 May 8;12(5):1339. doi: 10.3390/nu12051339. PMID: 32397163; PMCID: PMC7285126. Mallard B, Leach DN, Wohlmuth H, Tiralongo J. Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake. PLoS One. 2019 Nov 7;14(11):e0224740. doi: 10.1371/journal.pone.0224740. PMID: 31697749; PMCID: PMC6837746. Afshar K, Fleischmann N, Schmiemann G, Bleidorn J, Hummers-Pradier E, Friede T, Wegscheider K, Moore M, Gágyor I. Reducing antibiotic use for uncomplicated urinary tract infection in general practice by treatment with uva-ursi (REGATTA) - a double-blind, randomized, controlled comparative effectiveness trial. BMC Complement Altern Med. 2018 Jul 3;18(1):203. doi: 10.1186/s12906-018-2266-x. PMID: 29970072; PMCID: PMC6029138. Dandare SU, Ezeonwumelu IJ, Shinkafi TS, Magaji UF, Adio AA, Ahmad K. L-alanine supplementation improves blood glucose level and biochemical indices in alloxan-induced diabetic rats. J Food Biochem. 2021 Jan;45(1):e13590. doi: 10.1111/jfbc.13590. Epub 2020 Dec 21. PMID: 33346923. Sekhar, R. V., Patel, S. G., Guthikonda, A. P., Reid, M., Balasubramanyam, A., Taffet, G. E., & Jahoor, F. (2011). Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. The American journal of clinical nutrition, 94(3), 847–853. https://doi.org/10.3945/ajcn.110.003483 Razak, M. A., Begum, P. S., Viswanath, B., & Rajagopal, S. (2017). Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review. Oxidative medicine and cellular longevity, 2017, 1716701. https://doi.org/10.1155/2017/1716701 Bonaterra GA, Bronischewski K, Hunold P, Schwarzbach H, Heinrich EU, Fink C, Aziz-Kalbhenn H, Müller J, Kinscherf R. Anti-inflammatory and Anti-oxidative Effects of Phytohustil® and Root Extract of Althaea officinalis L. on Macrophages in vitro. Front Pharmacol. 2020 Mar 17;11:290. doi: 10.3389/fphar.2020.00290. PMID: 32256361; PMCID: PMC7090173. Goldenseal. (2021). In Drugs and Lactation Database (LactMed). National Library of Medicine (US). Mandal, S. K., Maji, A. K., Mishra, S. K., Ishfaq, P. M., Devkota, H. P., Silva, A. S., & Das, N. (2020). Goldenseal (Hydrastis canadensis L.) and its active constituents: A critical review of their efficacy and toxicological issues. Pharmacological research, 160, 105085. https://doi.org/10.1016/j.phrs.2020.105085 Mara de Menezes Epifanio, N., Rykiel Iglesias Cavalcanti, L., Falcão Dos Santos, K., Soares Coutinho Duarte, P., Kachlicki, P., Ożarowski, M., Jorge Riger, C., & Siqueira de Almeida Chaves, D. (2020). Chemical characterization and in vivo antioxidant activity of parsley (Petroselinum crispum) aqueous extract. Food & function, 11(6), 5346–5356. https://doi.org/10.1039/d0fo00484g Jovic, T. H., Ali, S. R., Ibrahim, N., Jessop, Z. M., Tarassoli, S. P., Dobbs, T. D., Holford, P., Thornton, C. A., & Whitaker, I. S. (2020). Could Vitamins Help in the Fight Against COVID-19?. Nutrients, 12(9), 2550. https://doi.org/10.3390/nu12092550 Traber, M. G., & Atkinson, J. (2007). Vitamin E, antioxidant and nothing more. Free radical biology & medicine, 43(1), 4–15. https://doi.org/10.1016/j.freeradbiomed.2007.03.024 Wu, D., & Meydani, S. N. (2014). Age-associated changes in immune function: impact of vitamin E intervention and the underlying mechanisms. Endocrine, metabolic & immune disorders drug targets, 14(4), 283–289. https://doi.org/10.2174/1871530314666140922143950 De la Fuente, M., Hernanz, A., Guayerbas, N., Victor, V. M., & Arnalich, F. (2008). Vitamin E ingestion improves several immune functions in elderly men and women. Free radical research, 42(3), 272–280. https://doi.org/10.1080/10715760801898838 Browne, D., McGuinness, B., Woodside, J. V., & McKay, G. J. (2019). Vitamin E and Alzheimer's disease: what do we know so far?. Clinical interventions in aging, 14, 1303–1317. https://doi.org/10.2147/CIA.S186760 Serving Size: 2 Capsules;Capsules Per Container: 60;Bottle Color: White;Bottle Size: 175cc;Lid Color: White * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Read more less

Formula Ingredient Deck Benefits Of Each Ingredient  Vitamin B6 Serves as a cofactor in more than 150 enzymatic reactions associated in blood sugar regulation, immunity, cardiovascular function, neuronal health, metabolic, and digestive health (38, 40). Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39) Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40) Passion Flower Extract Reduces stress, enhances sleep, and improves mood (248). Enhances positive mood and sleep via regulated gamma‐aminobutyric acid receptor A (GABAA) activity (receptor which controls sleep) (248). Melatonin Supports healthy sleep patterns, immune function, and antioxidant support (256,257, 258). Supports healthy circadian rhythms, and improves the onset, duration, and quality of sleep. Supports immune function via improved free radical scavenging capacity (258).   Proper Use of This Supplement Suggested Use: As a dietary supplement, take two (2) gummies before bedtime.   Our Formula VS Other Formulas on the Market 1. Uses third party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third party tested have been removed by FDA due to high levels of heavy metals. 2. Uses high quality nutraceuticals in an effective evidence based and efficaciously dosed formula. 2. Uses cheap sources of nutraceuticals that contain high amounts of fillers, heavy metals, and is formulated without evidence-based dosages.   CAUTION: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. KEEP OUT OF REACH OF CHILDREN.DO NOT USE IF SAFETY SEAL ISDAMAGED OR MISSING.STORE IN A COOL, DRY PLACE. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Read more less

Formula Ingredient Deck Benefits Of Each Ingredient  Turmeric · Supports antioxidant, cardio-protective, anti-inflammatory, anti-microbial, nephro-protective, hepato-protective, immunomodulatory, and anti-rheumatic effects (123). · Reduces inflammation via decreases of inflammatory markers such as c-reactive protein, interleukin 6, tumor necrosis factor, and decreased cytokine production (123). · Supports joint health via decreases in connective tissue inflammation and improved pain in individuals with osteoarthritis (122). · Supports blood sugar regulation via increased pancreatic beta cell function and improved insulin sensitivity (121).   Proper Use of This Supplement Suggested Use:  As a dietary supplement take two (2) gummies once a day.   Our Formula Vs Other Formulas on the Market. 1. Uses third party independently tested ingredients that are made in the USA, GMP certified, and made in an FDA registered facility. 1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third party tested have been removed by FDA due to high levels of heavy metals. 2. High quality turmeric in an effective and efficaciously dosed formula 2. Uses cheap sources of turmeric that contain high amounts of fillers and heavy metals. Sources Pivari, F., Mingione, A., Brasacchio, C., & Soldati, L. (2019). Curcumin and Type 2 Diabetes Mellitus: Prevention and Treatment. Nutrients, 11(8), 1837. https://doi.org/10.3390/nu11081837 Ashtary-Larky, D., Rezaei Kelishadi, M., Bagheri, R., Moosavian, S. P., Wong, A., Davoodi, S. H., Khalili, P., Dutheil, F., Suzuki, K., & Asbaghi, O. (2021). The Effects of Nano-Curcumin Supplementation on Risk Factors for Cardiovascular Disease: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical Trials. Antioxidants (Basel, Switzerland), 10(7), 1015. https://doi.org/10.3390/antiox10071015 Mata, I., Mata, S., Menezes, R., Faccioli, L. S., Bandeira, K. K., & Bosco, S. (2020). Benefits of turmeric supplementation for skin health in chronic diseases: a systematic review. Critical reviews in food science and nutrition, 1–15. Advance online publication. https://doi.org/10.1080/10408398.2020.1798353 SUGGESTED USE: As a dietary supplement take two (2) Gummies once a day. CAUTION: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. KEEP OUT OF REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. STORE IN A COOL, DRY PLACE. * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Read more less